[Hydrogen rich water attenuates pregnancy gingivitis induced by ligation in SD rats].

This animal study examined [Hydrogen rich water attenuates pregnancy gingivitis induced by ligation in SD rats]. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 2 weeks. The abstract reports: Progesterone and its receptor may play an indirect role in the process of pregnancy gingivitis of rats. Hydrogen rich water may be beneficial in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.

This animal study examined Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice. The abstract describes Mouse model; sample size 8. The abstract reports: Western blot analysis showed that coadministration of 1.3% hydrogen gas significantly (P < 0.001) reduced the level of neuronal apoptosis to approximately 40% compared…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment

This in vitro or cellular study examined Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. The abstract describes Fibroblast model; hydrogen delivered as hydrogen water. The abstract reports: Extract from HW-treated HGF cells scavenged ROO· more markedly than that from DDW-treated cells, suggesting that HW can increase the intracellular antioxidant capacity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents

This in vitro or cellular study examined Combined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents. The abstract describes Keratinocyte model; hydrogen delivered as hydrogen water. The abstract reports: Remarkably, the combined use of HW and EBND exhibited particularly robust results. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.

This animal study examined The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs. The abstract describes Animal model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: We observed that HRW wounds showed an increased rate of wound healing, and a faster average healing time compared with DW. This is an automated editorial draft based on the abstract and requires source review before publication.

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Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity

This animal study examined Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. The abstract describes Rat model; reported duration 28 days. The abstract reports: Hydrogen-dissolved water has been suggested to be effective for alleviating the oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation.

This animal study examined Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrate that HS restored behavioral deficits after HI in neonatal mice. These beneficial effects, in part, involve promoting microglia M2 polarization and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.

This animal study examined Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: We found that HRS administration was able to inhibit the acquisition and transfer of 0.1 and 0.5 mg/kg METH-induced behavioral sensitization to a certain extent,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model

This animal study examined Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. The abstract describes Mouse model. The abstract reports: We have previously demonstrated in the MIA mouse model that maternal administration of H attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring.

This animal study examined Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Due to its anti-inflammatory and anti-oxidative effects, recent research has demonstrated that molecular hydrogen can serve as a new medical approach for depression, anxiety…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway.

This animal study examined Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The result showed that HS administration alleviated HI-induced edema, infract volume and cellular apoptosis within the cortex of neonatal mice. Accompanying these indices of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of oral intake of hydrogen water on liver fibrogenesis in mice.

This animal study examined Effects of oral intake of hydrogen water on liver fibrogenesis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. The abstract reports: We conclude that hydrogen water protects hepatocytes from injury by scavenging hydroxyl radicals and thereby suppresses liver fibrogenesis in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Oral hydrogen water prevents chronic allograft nephropathy in rats.

This animal study examined Oral hydrogen water prevents chronic allograft nephropathy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Toxin-Contaminated Diet.

This animal study examined Intestinal Microbiota Ecological Response to Oral Administrations of Hydrogen-Rich Water and Lactulose in Female Piglets Fed a Toxin-Contaminated Diet. The abstract describes Porcine model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: Results showed that mycotoxins not only reduced the hydrogen levels in the caecum but also shifted the SCFAs production, and populations and communities of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Silicon nanoparticles for oral administration of molecular hydrogen.

This animal study examined Silicon nanoparticles for oral administration of molecular hydrogen. The abstract describes Animal model. The abstract reports: Silicon particles are suggested for oral administration with the ability to undergo a redox reaction with water to produce Hin vivo. This is an automated editorial draft based on the abstract and requires source review before publication.

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