[Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury].

This animal study examined [Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury]. The abstract describes Rat model; sample size 8; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Hydrogen inhalation can decrease the expression of TNF-α in the lung tissue and serum, and this effect may be related with reduced p38 MAPK…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.

This animal study examined Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Small amounts of inhaled hydrogen were superior to mild hypothermia in improving cardiac function and neurological outcome in this asphyxial rat model of cardiac…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players.

This randomized controlled trial examined Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 3 weeks. The abstract reports: Two-way (supplementation and time) repeated-measures analyses of variance showed that NO, L-arginine, and tetrahydrobiopterin levels in the H inhalation group were significantly higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway.

This uncontrolled human study examined Hydrogen inhalation therapy regulates lactic acid metabolism following subarachnoid hemorrhage through the HIF-1α pathway. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: The neuroprotective effects of hydrogen have been demonstrated, but the mechanism is still poorly understood. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis.

This animal study examined Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.

This uncontrolled human study examined Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.

This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.

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Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.

This animal study examined Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: H gas administration exerted a neuroprotective effect against early brain injury after ICH through anti-inflammatory, neuroprotective, anti-apoptotic, and antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.

This randomized controlled trial examined Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial. The abstract describes Human participants; sample size 39; hydrogen delivered as hydrogen inhalation. The abstract reports: The Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During Post-Cardiac Arrest Care (HYBRID) II trial (jRCTs031180352) suggested that hydrogen inhalation may…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.

This animal study examined Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our results suggest that hydrogen inhalation exerts an acute brain-protective effect in the mouse ICH model. However, the acute hydrogen therapy alone is not…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest

This uncontrolled human study examined Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: In this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.

This in vitro or cellular study examined Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: CV showed no significant improvement between the control and H groups. This is an automated editorial draft based on the abstract and requires source review before publication.

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Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.

This study protocol examined Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial. The abstract describes Planned or registered research population; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model

This animal study examined Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: The HI group (n = 10) showed a transient increase in SV and CO followed by a decline. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen inhalation promotes recovery of a patient in persistent vegetative state from intracerebral hemorrhage: A case report and literature review.

This case report or case series examined Hydrogen inhalation promotes recovery of a patient in persistent vegetative state from intracerebral hemorrhage: A case report and literature review. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Phase 1 clinical trials are needed to explore the safety and efficacy of H gas inhalation in patients with PVS. This is an automated editorial draft based on the abstract and requires source review before publication.

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