Postconditioning with inhaled hydrogen attenuates skin ischemia/reperfusion injury through the RIP-MLKL-PGAM5/Drp1 necrotic pathway.
This animal study examined Postconditioning with inhaled hydrogen attenuates skin ischemia/reperfusion injury through the RIP-MLKL-PGAM5/Drp1 necrotic pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: In the SH and HCH groups, the necrotic factors measured here showed similar expression levels, which were significantly lower than the levels in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSafety of inhaled hydrogen gas in healthy mice.
This animal study examined Safety of inhaled hydrogen gas in healthy mice. The abstract describes Mouse model; sample size 25; hydrogen delivered as hydrogen inhalation; reported duration 72 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
This randomized controlled trial examined Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection. The abstract describes Human participants; sample size 50; hydrogen delivered as hydrogen inhalation. The abstract reports: H treatment was safe and effective in patients with acute cerebral infarction. These results suggested a potential for widespread and general application of H…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFeasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
This uncontrolled human study examined Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study. The abstract describes Human participants; sample size 107; hydrogen delivered as hydrogen inhalation. The abstract reports: HI in combination with TTM is a feasible therapy for patients with PCAS. (Circ J 2016; 80: 1870-1873). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer Patients.
This observational study examined Pilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer Patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation. The abstract reports: H gas inhalation combined with CCRT is feasible and safe for patients with LAHNC. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China
This observational study examined Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 24 week. The abstract reports: The HI therapy is related to significant amelioration in BP levels with acceptable safety profile in Chinese hypertensive adults after 24 weeks of treatment,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation: in vivo rat genotoxicity tests.
This animal study examined Hydrogen inhalation: in vivo rat genotoxicity tests. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study
This uncontrolled human study examined Effectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study. The abstract describes Human participants; sample size 1088; hydrogen delivered as hydrogen inhalation; reported duration 6 month. The abstract reports: HI as an adjunct therapy ameliorates glycemic control, lipid metabolism, insulin resistance and AE incidence of T2DM patients after 6-month treatment, presenting a noteworthy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreReal-World Effectiveness and Safety of Hydrogen Inhalation in Chinese Patients with Type 2 Diabetes: A Single-Arm, Retrospective Study.
This observational study examined Real-World Effectiveness and Safety of Hydrogen Inhalation in Chinese Patients with Type 2 Diabetes: A Single-Arm, Retrospective Study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: HI therapy significantly improves glycemic control, weight, insulin dose, lipid metabolism, β-cell function and insulin resistance of patients with type 2 diabetes after 6…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorates ventilator-induced lung injury.
This uncontrolled human study examined Hydrogen inhalation ameliorates ventilator-induced lung injury. The abstract describes Human participants; sample size 8; hydrogen delivered as hydrogen inhalation; reported duration 2 hours. The abstract reports: Inhaled hydrogen gas effectively reduced VILI-associated inflammatory responses, at both a local and systemic level, via its antioxidant, anti-inflammatory and antiapoptotic effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice.
This animal study examined Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings demonstrated that H inhalation could inhibit CS-induced COPD development in mice, which is associated with reduced ERK1/2 and NF-κB-dependent inflammatory responses. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits.
This animal study examined Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen inhalation. The abstract reports: These results demonstrate that hydrogen gas inhalation attenuates seawater instillation-induced acute lung injury in rabbits and that the protective effects observed may be related…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation.
This animal study examined Hydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 2% hydrogen gas after HSR minimized the extent of lung injury by decreasing MPO activity and reducing infiltration of inflammatory cells into…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
This animal study examined Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. The abstract describes Rat model; sample size 15; hydrogen delivered as hydrogen inhalation. The abstract reports: Combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.
This animal study examined Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating…. This is an automated editorial draft based on the abstract and requires source review before publication.
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