Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In a laboratory model, compared to HRW and CaH2, OSHCs demonstrated a prolonged reduction in ORP for 60 minutes in vitro and enabled a regulated release of hydrogen over 24 hours. The authors concluded that oSHCs supplementation may exert anti-inflammatory and antioxidant…
Read ArticleThe results suggested that t-Tau and p-Tau levels were significantly reduced after 4 weeks of H₂ gas inhalation treatment, which was effective for improved neurodegenerative diseases, such as…
Read ArticleIn mice, 2 Treatment with 2% hydrogen improved the 7-day survival rate and decreased the levels of inflammatory cytokines in septic mouse cortex tissues. These preclinical findings add…
Read ArticleIn C57BL/6 mice, western blotting showed that hydrogen treatment reduced Bax and TNFα levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleThe researchers found that 2% H₂ inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at 5 CpG sites,…
Read ArticleIn contrast, catalase and GPx activities were significantly increased in the TMT-only group and decreased after H₂ gas treatment in serum and brain. These preclinical findings add evidence…
Read ArticleThe results of the study showed that anterior fontanel tension, disturbance of consciousness, muscle tone, primitive reflex recovery time, and convulsion control time were significantly decreased in the…
Read ArticleIn 184 patients, the numerical rating scale (NRS) pain scores were higher in the hydrogen group (4.08 ± 1.77) than the control group (3.54 ± 1.77) on day…
Read ArticleThe researchers found that hydrogen-rich saline reduced the severity of EAE in mice and alleviated inflammation and demyelination. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, aNOVA with percentage of exploration time spent in the target quadrant revealed a significant effect of METH (F (1,31) = 24.930, p < 0.001) and ad…
Read ArticleIn rats, surgery-challenged animals showed significant cognitive impairment evidenced by a decreased percentage of freezing time and an increased number of learning trials on days 1, 3, and…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn mice, the introduction of hydrogen-rich saline (group PH) partially rescued spatial memory and learning as it shortened escape latency and increased time and crossing frequency of original…
Read ArticleThe researchers found that H₂ can improve survival in septic mice, decrease escape latency and platform crossing times, decrease pro-inflammatory cytokines and oxidative product levels in the mouse…
Read ArticleIn male Wistar rats, hypothesized that inhaled H₂ decreases LPS-induced hippocampal pro-inflammatory cytokines surges and this effect is associated with reduced memory loss. These preclinical findings add evidence…
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