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Latest Molecular Hydrogen Articles

939 Articles

Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents.

By H2HUBB Jul 22, 2026 0 Comments

In conclusion, HW showed a possibility of repressing oxidative stress, inflammatory response, and adipogenesis at cellular/tissue levels. These findings from a laboratory model add evidence about molecular hydrogen's biological effects in the model studied. Hydrogen nanobubble water was the intervention; hydrogen peroxide…

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Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.

By H2HUBB Jul 22, 2026 0 Comments

In 0 patients with potential metabolic syndrome, serum analysis showed that consumption of H₂-rich water for 10 weeks resulted in decreased serum total-cholesterol (TC) and LDL-cholesterol (LDL-C) levels.…

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Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.

By H2HUBB Jul 22, 2026 0 Comments

In rats, serum levels of (E) FBG and (F) FINS. (G) Results of the ISI and HOMA -IR measurements. (I) Insulin tolerance test; after insulin administration, blood glucose…

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Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.

By H2HUBB Jul 22, 2026 0 Comments

In rats, maximum intracavernous pressure in diabetic rats decreased significantly compared to controls and increased significantly compared to untreated diabetic rats after hydrogen-rich saline treatment. These preclinical findings…

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Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study.

By H2HUBB Jul 22, 2026 0 Comments

In participants with IFG were enrolled in a randomized, H₂ slightly improved metabolic abnormalities and gut microbiota dysbiosis, providing a novel target and theoretical basis for the prevention…

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Adjunctive Molecular Hydrogen Therapy Modulates T Cell Markers and Reduces Anti-Ro Antibody in Refractory Oral Ulcers of Behçet’s Disease and Sjögren’s Syndrome: A Case Report.

By H2HUBB Jul 22, 2026 0 Comments

In Primary Sjögren's Syndrome is an autoimmune disorder mainly targeting exocrine glands, especially the salivary and lacrimal glands, with possible systemic involvement, by August 2025, oral ulcers had…

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Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents.

By H2HUBB Jul 22, 2026 0 Comments

In mice, first examined the H₂ concentrations in blood and organs after its administration and found that oral intake of HRW rapidly but transiently increased H₂ concentrations in…

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Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rat smooth muscle cell (A7r5) cultures, hydrogen treatment for 24 h reduced smooth muscle cell migration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

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Effects of hydrogen-rich water on aging periodontal tissues in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, four-month-old male Fischer 344 rats (n = 12) were divided into two groups: the experimental group (hydrogen-rich water treatment) and the control group (distilled water treatment).…

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Efficacy of Oral Intake of Hydrogen-Rich Jelly Intake on Gingival Inflammation: A Double-Blind, Placebo-Controlled and Exploratory Randomized Clinical Trial.

By H2HUBB Jul 22, 2026 0 Comments

These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.

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Using oral molecular hydrogen supplements to combat microinflammation in humans: a pilot observational study.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, compared to HRW and CaH2, OSHCs demonstrated a prolonged reduction in ORP for 60 minutes in vitro and enabled a regulated release of hydrogen…

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Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial.

By H2HUBB Jul 22, 2026 0 Comments

The results suggested that t-Tau and p-Tau levels were significantly reduced after 4 weeks of H₂ gas inhalation treatment, which was effective for improved neurodegenerative diseases, such as…

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Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner.

By H2HUBB Jul 22, 2026 0 Comments

In mice, 2 Treatment with 2% hydrogen improved the 7-day survival rate and decreased the levels of inflammatory cytokines in septic mouse cortex tissues. These preclinical findings add…

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Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model.

By H2HUBB Jul 22, 2026 0 Comments

In C57BL/6 mice, western blotting showed that hydrogen treatment reduced Bax and TNFα levels. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…

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Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice.

By H2HUBB Jul 22, 2026 0 Comments

The researchers found that 2% H₂ inhalation can reduce pro-inflammatory factors, alleviate DNMT1, DNMT3a but not DNMT3b expression, make hypomethylation of BDNF promoter IV at 5 CpG sites,…

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