Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, H₂ preconditioning improved liver function and antioxidant status while reducing inflammation and liver injury during CO₂ pneumoperitoneum. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn rats, these data suggested that pharmacological postconditioning with lactic acid and hydrogen rich saline nearly replicates the benefits of mechanical postconditioning. These preclinical findings add evidence supporting…
Read ArticleThe researchers found that the beneficial effects of hydrogen-rich saline treatment were associated with decreased levels of oxidative products (8-iso-prostaglandin F2α and malondialdehyde) and inflammatory cytokines (tumor necrosis…
Read ArticleIn male Sprague-Dawley rats, sTZ-diabetic rats were marked by clearly reduced b-wave amplitudes and oscillatory potentials, DM-related BRB breakdown and histological changes in the inner retina, all of…
Read ArticleIn 34 healthy participants, CO₂/H₂ cold-water immersion helped preserve isometric strength, countermovement-jump height, and range of motion after eccentric exercise compared with the other recovery conditions. Muscle soreness…
Read ArticleIn rats, maximum intracavernous pressure in diabetic rats decreased significantly compared to controls and increased significantly compared to untreated diabetic rats after hydrogen-rich saline treatment. These results are…
Read ArticleHydrogen-rich saline did not obviously ameliorate the signs of uveitis under slit lamp examination and the inflammatory cells infiltration around iris and cilliary body of EIU induced by…
Read ArticleIn Caco-2 cells were exposed to different concentrations of LPS (1 μg/mL-1 mg/mL), lPS (100 μg/mL) decreased TER and increased fluorescein-isothiocyanate-dextran flux, which were alleviated by H₂-rich medium.…
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The publication summarizes the rationale and available evidence for molecular hydrogen, but it does not by itself prove treatment effectiveness. Hydrogen-rich saline research study 2023:…
Read ArticleHydrogen improved microvascular endothelial-cell viability partly through PI3K/Akt/GSK3β activation and inhibition of autophagy in a traumatic-brain-injury model. These findings come from a laboratory model and suggest molecular hydrogen's…
Read ArticleIn an animal model, focused on the mechanism and role of autophagy and inflammasome, by which hydrogen alleviated the hyperpathia induced by neuropathic pain. These preclinical findings add…
Read ArticleIn male Wistar rats, compared with those in isoproterenol-MI group, hydrogen-rich saline decreased malondialdehyde and 8-hydroxy-desoxyguanosine concentrations, enhanced superoxide dismutase and Na(+)-K(+)-ATPase activity, lowered Ca(2+)-ATPase activity and decreased…
Read ArticleIn an animal model, the incidence of bacterial translocation at 24 h after CLP as assessed by cultivation of mesenteric lymph nodes and blood was significantly decreased in…
Read ArticleIn rats, molecular hydrogen can easily attach to biomembranes and enter cytosol, mitochondria and other organelles of the cell and convert the formed OH- to H₂O to prevent…
Read ArticleIn rats, at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration, serum malondialdehyde content,…
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