Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, the lung injury score determined by histopathology, the cell apoptotic index, and the caspase-3 protein expression in lung grafts were decreased after hydrogen treatment, and the static pressure-volume curve of lung graft was improved by hydrogen inflation. These preclinical findings…
Read ArticleIn rats, hydrogen improved PaO(2)/FIO(2) and PVO(2)/FIO(2) from the arterial and pulmonary venous blood in recipients and decreased the lung injury score in grafts from brain-dead donors. These…
Read ArticleIn rabbits, after 240 min of reperfusion, intraperitoneal administration of HRS increased PaO2/FiO2 ratio and superoxide dismutase activities, and decreased malondialdehyde contents, proinflammatory cytokines expression, and myeloperoxidase activities,…
Read ArticleIn rats, the intracellular surfactant pool, tissue adenosine triphosphate (ATP) levels and heat shock protein 70 (HSP70) expression increased in the hydrogen-treated grafts. These preclinical findings add evidence…
Read ArticleIn a laboratory model, H₂ suppressed the expression of HIF1α and PDK1, suggesting that H₂ may act upstream of hypoxia-driven signaling pathways. The authors concluded that the findings…
Read ArticleIn rats, through transmission electron microscopy, the researchers observed that the GSDMD membrane pores in AMs were increased at 12 and 24 h post-burn compared with sham rats;…
Read ArticleIn a laboratory model, hydrogen administration also promoted mitochondrial biogenesis and significantly decreased lactate production. The authors concluded that preconditioning lung grafts using inhaled hydrogen attenuated these proinflammatory…
Read ArticleThese findings add human evidence supporting molecular hydrogen's therapeutic potential to influence fatigue-related outcomes.
Read ArticleBased on a review of the research, the use of hydrogen might reduce the destructive cytokine storm and lung injury caused by SARS-CoV-2 during COVID-19 (Corona Virus Disease…
Read ArticleIn a laboratory model, the protective effect of hydrogen (H(2)) on ROS-induced diseases has been proved by many researches, which demonstrated that through eliminating •OH and •ONOO-, H(2)…
Read ArticleIn vitro, LPS treatment increased the expression levels of STIM1 and Orai1 in PMVECs, while H₂ reversed these changes. The authors concluded that the present study suggested that…
Read ArticleIn rats, exposure to 2% H₂ significantly blocked the production of several proinflammatory mediators and reduced apoptosis with induction of the antiapoptotic molecules B-cell lymphoma-2 and B-cell lymphoma-extra…
Read ArticleIn rats, aRP decreased body weight, increased the lung coefficient, collagen deposition and macrophage infiltration and promoted M1 polarization in rats. These preclinical findings add evidence supporting molecular…
Read ArticleThis narrative review examined the biological rationale and early clinical evidence for oxy-hydrogen inhalation in respiratory conditions. The authors highlighted early evidence of cytoprotective, antioxidant, and anti-inflammatory effects.…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read Article