Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, tumor necrosis factor-alpha (TNF-α) levels, malondialdehyde (MDA) concentrations, nuclear factor kappa B (NF-κB) p65 expression, and apoptosis index (AI) in I+HS group were significantly decreased (P < 0.05), while superoxide dismutase (SOD) activities were increased compared with those…
Read ArticleIn 5 patients with mild-to-moderate, HRW was not superior to placebo in preventing clinical worsening at day 14: in the H₂ group, 46.1% in the H₂ group, 43.5%…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Biological gaseous molecules including nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (H2S), and molecular hydrogen (H₂) have been found…
Read ArticleThis narrative review examined the types of H₂ donors and their pharmacokinetics in vivo. There are various methods of administration of H₂, mainly including inhaling hydrogen gas, drinking…
Read ArticleIn 0 patients with progressive muscular dystrophy (PMD), less prominent effects with the double-blind trial compared to the open-label trial were likely due to a lower amount of…
Read ArticleIn rats, lactulose increased breath hydrogen concentrations in 86% of healthy participants and 59% of PD patients. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn rats, hydrogen saline significantly reduced the infarct volume and edema and improved the neurological function, when it was administered at 0, 3 and 6 h after reperfusion.…
Read ArticleThis publication examined molecular hydrogen using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn an animal model, the inhalation of 42% H₂ for one hour per day for 48 h significantly reduced brain edema, decreased the extravasation of sodium fluorescein, and…
Read ArticleIn mice, hydrogen inhalation significantly reduced infarct volume, attenuated brain edema and improved neurobehavioral deficit in MCAO mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn 5 patients, lPO slightly increased at 3 h after the initiation of H₂ gas inhalation but was then maintained over 24 h. These findings add human evidence…
Read ArticleThis narrative review examined the patient finally recovered to a near normal conscious state with a Coma Recovery Scale-Revised Score of 22 from his previous score of 3.…
Read ArticleIn 2 participants, this case has demonstrated that intensive consecutive therapy with oral transmucosal hydrogen formulation is a beneficial strategy with regard to the reduction of presence and…
Read ArticleIn mice, local treatment of hydrogen-rich water shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. These preclinical findings add evidence supporting molecular…
Read Article