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In mice, further, the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-12p70 in ERW group decreased whereas those of IL-10 increased. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this…
Read ArticleThe results also revealed that H₂ suppressed H₂O₂-induced increases in intracellular peroxide and H₂O₂ levels, and suppressed the progression of lipid peroxidation. The authors concluded that taken together,…
Read ArticleIn mice, the relative expression level of caspase-3 protein in skin specimens of cGVHD mice increased to 7.17 on the 96th day after transplantation, significantly higher than 4.36…
Read ArticleThis animal study examined Hydrogen peroxide in neutrophil inflammation: Lesson from the zebrafish. The abstract describes Zebrafish model. The abstract reports: Therefore, these results have pointed out DUOX1…
Read ArticleIn mice, H₂ remarkably decreased ROS accumulation and enhanced antioxidant enzymes activities by up-regulating expression of Nrf2 and its downstream components in wound tissue and/or H₂O₂ -treated endothelia.…
Read ArticleIn rats, the production of proinflammatory cytokines in inflamed colon tissue was also decreased significantly. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn mice, hRS increased the levels of TGF-β and PCNA. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in…
Read ArticleInterestingly, the use of a hydrogen-rich medium significantly reduced the level of intracellular O(2)(-), stabilized the ΔΨ and attenuated production of MDA, 8-OHdG and 3-NT which efficiently enhanced…
Read ArticleIn an animal model, hydrogen-rich water used for prevention or treatment of oxidative stress-related diseases in oral cavity 3: The study was conducted to investigate protective effects of…
Read ArticleIn mice, marked aggression of the tumors was found, leading to the possibility that hyperbaric hydrogen therapy might also prove to be of significance in the treatment of…
Read ArticleIn male HR-1 hairless mice, H₂ preserved the GSH/GSSG ratio following acute UVB exposure and reduced nuclear Nrf2 accumulation during chronic exposure. These preclinical findings add evidence supporting…
Read ArticleIn Sprague Dawley rats, mDA and 8-OHdG were significantly decreased in hydrogen-rich medium, while SOD and GSH were increased. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn 3 patients, iL-17, whose concentration was high in Case 1, was reduced following H₂ treatment, and TNFα also decreased in Case 1. These findings add human evidence…
Read ArticleIn Decreased Ca2+ signaling is observed in aged cells, probably secondary to the formation of disulfide bonds among Ca2+ signaling-related proteins,, skin aging processes may involve ROS-induced protein…
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