Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. H₂ is readily available because it has minimal harmful effects and is highly effective against nearly all pathogenic states related to oxidative stress and inflammation. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn an animal model, 0.89mM HRW also reduced disease severity, CNS infiltration, and demyelination when administered after the onset of disease. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, the mRNA expression of hypoxia-inducible factor 1 alpha and its immediate downstream target vascular endothelial growth factor (VEGF) showed significant elevation after laser, and this elevation…
Read ArticleIn rats, similarly, coenzyme Q9 levels in the rat plasma, myocardial tissue, and mitochondria were increased and malondialdehyde level in plasma was reduced after HRW administration. These preclinical…
Read ArticleIn rats, however, compared with the control group, exposure to 3% hydrogen significantly improved lung graft static compliance and oxygenation and remarkably decreased the wet-to-dry weight ratio, inflammatory…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. These responses are able to increase tissue damage and even damage to the whole body. The reviewed evidence adds support…
Read ArticleIn the ischemia-reperfusion hydrogen-rich water group, PI3K, AKT and p-AKT mRNA and protein expression levels were increased while the FoxO1, Bim and Caspase-3 expression levels were significantly decreased…
Read ArticleIn male Wistar rats, experiments on isolated aortic preparations from MCT rats showed that the addition of H₂ to the perfusion medium resulted in a 30% reduction in…
Read ArticleIn vitro experiments showed that hydrogen-rich medium mitigated the CT-1-induced cardiomyocyte hypertrophy with a similar effect as the JAK specific antagonists AG490. These preclinical findings add evidence supporting…
Read ArticleIn rats, vIP (OPLS-DA) analysis was performed with T test, and the metabolites of the control group and the hydrogen-rich water group were significantly different, and the glycerophospholipid…
Read ArticleThe results confirmed the protection of HRS in LPS-induced ALI by regulating apoptosis through inhibiting the mTOR/TFEB signaling pathway. These findings from a laboratory model add evidence supporting…
Read ArticleThe results demonstrated that treatment with hydrogen improved the myocardial infarction size of hearts, cardiac function, apoptosis and cytokine release following MI/R in rats. The authors concluded that…
Read ArticleIn In vitro effects of hydrogen on fetal bovine serum (FBS)-induced vascular smooth muscle cell (VSMC) proliferation were also investigated, 7D shows that treatment with HRM significantly inhibited…
Read ArticleIn 39 participants, the interventions of molecular hydrogen (H₂) and app-based heart rhythm biofeedback (HRV-BF) did not yield improvements across conditions; however, pre–post improvements in physical function and…
Read ArticleThis in vitro or cellular study examined Hydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition. The abstract describes Endothelial cell model. The abstract reports: Our…
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