H2HUBB SCIENTIFIC RESOURCE
Molecular Hydrogen Research Library
Explore molecular hydrogen research collected and organized by H2HUBB over more than a decade. Search studies by condition, evidence type, delivery method, author, journal, DOI, or PMID.
Library last updated: September 21, 2026
This library summarizes published research for educational purposes. A study listing does not establish safety, effectiveness, or medical suitability for an individual.
THE STORY BEHIND THE LIBRARY
Built from More Than a Decade of Research
The H2HUBB Molecular Hydrogen Research Library is a public collection of scientific publications gathered and organized by H2HUBB founder Tywon Hubbard over more than a decade of work in the molecular hydrogen field. These are sources he has used in research, education, product evaluation, and professional work, now made available in one searchable public resource.
This library reflects H2HUBB’s commitment to locating original sources, preserving accurate study information, and helping researchers, professionals, and consumers better understand the developing science of molecular hydrogen.
FAVORABLE STUDY OUTCOMES
What the Published Research Reports
These percentages are based on assessable published study outcomes. Positive and mixed/partially positive outcomes are counted as favorable.
Methodology
Whole-library favorable outcome: (1,217 positive + 137 mixed/partially positive) ÷ 1,359 assessable primary outcome studies = 99.6%.
Human favorable outcome: 136 ÷ 144 assessable human-participant primary outcome studies = 94.4%.
Reviews, protocols, mechanistic-only records, and primary studies without a defensible directional outcome do not enter the favorable-outcome denominator.
BROWSE THE DATABASE
Explore Molecular Hydrogen Research by Topic
RESEARCH RESULTS
2,044 Studies Found
Hydrogen therapy and cardiovascular diseases: a visualization analysis of research hotspots and application prospects.
Yi Qian, Mingfei Shi, Yan Yang, Wei Qian, Ziyun Li, Jingqing Hu · Medical gas research · 2027
The review reports that The information was analyzed using Excel 2019, OriginPro 2024, VOSviewer 1.6.20 and CiteSpace 6.2.
Molecular hydrogen: a potential guardian against environmental radiation damage.
Yusuke Ichikawa, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh · Medical gas research · 2027
The review reports that In contrast, hydrogen can intervene at the stage of preventing biomolecular damage induced by environmental radiation and provide comprehensive protection at the tissue and cellular levels, uniquely minimizing…
Molecular hydrogen and osteoarthritis: multi-target mechanisms and therapeutic effectiveness.
Jiayu Chen, Dong Pan, Yixiang Zhao, Junyu Lin, Jie Tong · Medical gas research · 2027
The review reports that This review summarizes the multi-target mechanisms of molecular hydrogen and highlights innovative delivery technologies designed to overcome its key pharmacokinetic limitations, especially rapid diffusion and short residence time…
HydroMg attenuates doxorubicin-induced myocardial injury via promoting mitochondrial function.
Lu Zhang, Yawei Jin, Yuning Zhang, Mohan Li, Xiong Gao, Bin Ma, Xiaonan Ning, Aijun Sun, Wenjiang Ding, Zhiguang Ding, Xiurui Ma, Xiaolei Sun, Jian An · Medical gas research · 2027
In this animal study, the authors report that In vitro studies showed that 1 μg/mL HydroMg treatment attenuated doxorubicin-induced cardiomyocyte death by inhibiting apoptosis, reducing reactive oxygen species production, and restoring mitochondrial membrane potential.
Hydrogen-rich water combined with traditional Chinese medicine compound in the treatment of kidney stones: a randomized controlled prospective clinical trial.
Yu Yin, Jing Wang, Feng Lian, Yunqing Tang, Yidi Shen, Yue Guo, Qiming Xu, Jing Hu, Guobin Yang, Hongtao Lu, Wenrui Liu · Medical gas research · 2027
The study reports that The study was registered at the International Traditional Medicine Clinical Trial Registry (Registration No.
In situ-built chemo-electroactive hydrogel incorporating Mg-based hydrogen generators for osteoarthritis therapy.
Hongyu Zhong, Qi He, Fang Qin, Yao Shu, Yijian Wang, Xiang Yang, Zhonghao Chen, Sheng Yao, Chuxuan Gui, Jing Xiang, Lu Liu, Yun Chen, Yingfeng Tu, Kun Liu, Jinghui Yao · Materials today. Bio · 2026
The study reports that 4 We innovatively developed the microenvironment-responsive, chemo-electroactive PHO-MHG@BP hydrogel with favorable injectability and self-healing capability.
Upconversion nanocomposite for ROS-responsive diagnosis and hydrogen therapy of osteoarthritis
He, Baohua, Yang, Jing, Zhang, Jin · Frontiers in Materials · 2026
The study reports that A H2O2-sensitive thioketal (TK) linker was then conjugated onto the surface of UCNP@TiO2 to attach a black hole quencher (BHQ), yielding the functionalized nanocomposite UCNP@TiO2-TK-BHQ.ResultsIn the presence of…
Recent advances in chemically controlled molecular hydrogen generation for biomedical applications
Yu Zhao, Zhengbo Wang, Hongbin Li, Feng Cheng · Materials Today Chemistry · 2026
The review reports that These chemically controlled strategies enable selective regulation of highly reactive oxygen and nitrogen species.
An intelligent inflammation-responsive hydrogel for localized and sustained co-delivery of hydrogen and magnesium ions to regenerate degenerative intervertebral discs
Dan Li, Wanrong Yang, Jishi Jiang, Yifei Li, Wei Jiao, Hongliang Wang, Donglin Fu, Yunpeng Wan, Haiyang Yu, Yongjin Sun · Materials & Design · 2026
In this laboratory study, the authors report that This photocrosslinkable hydrogel enables minimally invasive injection and in situ gelation, forming a stable implant that undergoes matrix metalloproteinase (MMP)-triggered degradation within the degenerative disc microenvironment,…
Hydrogen inhalation in combat sport athletes: an overview of physiological and performance-related outcomes
Oxana Povarova, Marine Shirinyan, Aleksey A. Uzhakov, Olga L. Konnova, Oleg S. Medvedev · Functional Foods in Health and Disease - Online ISSN: 2160-3855; Print ISSN: 2378-7007 · 2026
The study reports that Hydrogen inhalation demonstrated beneficial effects on cardiovascular function, blood coagulation, and alkaline phosphatase levels.
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