Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 431 patients with type 2 diabetes mellitus (T2DM), higher baseline HbA1c level and shorter diabetes duration is related to greater clinical response to HI. These findings add human evidence that helps define the outcomes that did and did not change with…
Read ArticleIn 60 participants with hypertension aged 50-70 years, when stratified by age (aged 50-59 years versus aged 60-70 years), participants in the older H₂-O₂ group showed a larger…
Read ArticleIn an animal model, significantly higher partial pressure of arterial oxygen and significantly lower partial pressure of carbon dioxide were observed in the H₂ group than in the…
Read ArticleIn mice, inhaled hydrogen gas effectively reduced VILI-associated inflammatory responses, at both a local and systemic level, via its antioxidant, anti-inflammatory and antiapoptotic effects. These preclinical findings add…
Read ArticleThe results indicated that 2% H₂ gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the injuries caused by oxidative…
Read ArticleIn rats, as shown in this study, a reduction of TNF-α and IL-1β by 2% hydrogen gas inhalation may ultimately reduce the incidence of lung injury from the…
Read ArticleIn mice, as a result, Apoa2 protein or mRNA was identified as a target biomarker for H₂ with a protective, causal relationship with sepsis. These preclinical findings add…
Read ArticleIn 6 patients with chronic obstructive pulmonary disease (COPD), however, no significant differences were observed in lung function, DLCO, sleep quality, and 6 MWT before and after hydrogen…
Read ArticleIn mice, compared with the Sham group, mitochondrial dysfunction was alleviated in hydrogen groups. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn male C57BL/6 mice, hydrogen inhalation also significantly reduced inflammatory cytokine and chemokine mRNA levels and improved oxygenation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, hydrogen inhalation increased the survival rate to 80%, reduced LPS-induced lung damage, and decreased inflammatory cytokine release in LPS mice. These preclinical findings add evidence supporting…
Read ArticleThe results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury. These preclinical findings add evidence supporting…
Read ArticleIn an animal model, hydrogen treatment during exposure to hyperoxia significantly improved blood oxygenation, reduced inflammatory events, and induced HO-1 expression. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, hydrogen gas did not alleviate LPS-induced liver injury under the conditions tested. These results are preclinical and suggest that molecular hydrogen did not improve the measured…
Read ArticleIn an animal model, sepsis-challenged animals had decreased survival rate, as well as had increased bacterial burden in blood, peritoneal lavage, and lung sample, which were significantly ameliorated…
Read Article