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Latest Molecular Hydrogen Articles

1,249 Articles

Microbial hydrogen economy alleviates colitis by reprogramming colonocyte metabolism and reinforcing intestinal barrier.

By H2HUBB Jul 28, 2026 0 Comments

In mice, exogenous H₂ reprograms colonocyte metabolism by regulating the H₂-gut microbiota-SCFAs axis and strengthens the intestinal barrier by modulating specific mucosa-associated mucolytic bacteria, wherein improved microbial hydrogen economy alleviates colitis. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

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New Approaches for Hydrogen Therapy of Various Diseases.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. To solve the low solubility issue of hydrogen, a variety of nanomaterials and devices for hydrogen supply have recently been…

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Hydrogen-rich saline alleviates cardiomyocyte apoptosis by reducing expression of calpain1 via miR-124-3p.

By H2HUBB Jul 28, 2026 0 Comments

In mice, it was also found that compared with the HRS group, overexpression of calpain1 increased caspase-3 activities, promoted cleaved-caspase3 and Bax protein expressions, and correspondingly decreased Bcl-2,…

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Hydrogen: An Endogenous Regulator of Liver Homeostasis.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.

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Molecular hydrogen triggers TRPC4-TRPC4AP-dependent reversible calcium transients via extracellular influx.

By H2HUBB Jul 28, 2026 0 Comments

In C57BL/6 mice, exposure to saturated H₂ (1.6 mg/L) 38 rapidly increased cytoplasmic Ca 2+ concentration (Figure 1 A), reaching a peak within 30 s (F/F 0 =…

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Recent advances in hydrogen research as a therapeutic medical gas.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a…

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[Protective effects of hydrogen-rich medium on lipopolysaccharides-induced injury in human periodontal ligament cells].

By H2HUBB Jul 28, 2026 0 Comments

In a laboratory model, cCK-8 results showed that hydrogen could significantly improve hPDLCs growth and decrease cellular apoptosis under LPS stimulation (P<0.05). The authors concluded that the hydrogen-rich…

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The transfer of hydrogen from inert gas to therapeutic gas.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. More recent studies have shown that molecular hydrogen as a kind of antioxidant, anti-inflammatory, anti-apoptosis, gene expression and signal modulation…

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Cigarette smoke exposure impairs reverse cholesterol transport which can be minimized by treatment of hydrogen-saturated saline.

By H2HUBB Jul 28, 2026 0 Comments

In mice, cS exposure significantly decreased plasma HDL cholesterol level (HDL-C) by 22% and increased LDL cholesterol level (LDL-C) by 21% compared with the control group (p <…

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Effects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma.

By H2HUBB Jul 28, 2026 0 Comments

In 120 participants, larger multicenter studies in glioma populations, such as those in Parkinson's disease ( 2 ), are essential to validate these findings across diverse demographics and…

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Effects of hydrogen on polarization of macrophages and microglia in a stroke model.

By H2HUBB Jul 28, 2026 0 Comments

In This study aimed to investigate the effects of hydrogen gas on the polarization of macrophages/microglia in vitro, however, the hydrogen can reduced this impact to the normal…

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Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells.

By H2HUBB Jul 28, 2026 0 Comments

The results demonstrated that Pg LPS increased interleukin (IL) 1 alpha (IL-1α) and IL-6 secretion, but H₂ significantly suppressed the secretion of both cytokines without cytotoxicity. These findings…

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The potential utilizations of hydrogen as a promising therapeutic strategy against ocular diseases.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. It is the authors' hope that the protective effects of hydrogen, as evidenced by these pioneering studies, would enrich the…

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Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.

By H2HUBB Jul 28, 2026 0 Comments

This narrative review examined the available molecular-hydrogen literature. Hydrogen can also be used for prevention and treatment of various ageing-related diseases, such as neurodegenerative disorders, cardiovascular disease, pulmonary…

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Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles.

By H2HUBB Jul 28, 2026 0 Comments

In rats, H₂, Pt NPs and their combination significantly suppressed the levels of fasting blood glucose and improved the impaired sugar tolerance abilities of obese insulin-resistant type 2…

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