Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. Many studies demonstrate the safety of alkaline-electrolyzed-reduced water (ERW); however, several animal studies have reported significant tissue damage and hyperkalemia after drinking ERW. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across…
Read ArticleThe researchers observed that the combined protective effect of hydrogen and oxygen was superior to their respective protective effects, and the specific molecular mechanisms of the two therapies…
Read ArticleIn 4 patients, erythema of these 4 patients and associated symptoms improved significantly after the H₂ treatment and did not recur. These findings add human evidence supporting molecular…
Read ArticleIn 38 patients with acute cerebral infarction, analysis of urine sampling and plain chest X-rays showed no indications of pulmonary or urinary tract infection induced by the administration…
Read ArticleIn the present study, neutral-pH hydrogen-enriched electrolyzed water (NHE-water; dissolved hydrogen: 0.90-1.14 parts per million [ppm]; oxido-reduced potential: -150 approximately -80 mV), which was prepared with a water-electrolysis…
Read ArticleThis human publication evaluated hydrogen gas in 2014 patients with out-of-hospital cardiac arrest achieved spontaneous return of circulation. This pilot study suggests therapeutic potential, while larger randomized, placebo-controlled…
Read ArticleIn mice, hydrogen-rich saline treatment also significantly decreased mucus index, collagen deposition, and expression of MUC5AC, collagen III and VEGF. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleHydrogen inhalation was associated with greater reductions in systolic and diastolic blood pressure than control treatment through 24 weeks.
Read ArticleIn an animal model, no change in the PH or composition of the solution was observed due to hydrogen filling. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleThis meta-analysis examined the available evidence on molecular hydrogen. The meta-analysis found no significant effect on aerobic endurance, anaerobic endurance, or muscular strength, but reported a small improvement…
Read ArticleIn participants, the pooled effect sizes of H₂ on RPE (SMDpooled = -0.38, 95%CI -0.65 to -0.11, p = 0.006, I 2 = 33.6%, p = 0.149) and…
Read ArticleIn participants with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), there was a significant reduction of Cough Assessment Test score in Hydrogen/oxygen group compared to control (-…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline treatment decreased the neutrophil infiltration, the lipid membrane peroxidation, NF-kappaB activation and the pro-inflammatory cytokine interleukin IL-1beta and TNF-alpha in the lung…
Read ArticleIn rabbits, hydrogen gas inhalation markedly improved lung endothelial permeability and decreased both MDA content and MPO activity in lung tissue; these changes were associated with decreases in…
Read ArticleIn rats, low expression of AhR in lung tissues determined by Western Blot was found after CAPs exposure, whereas hydrogen inhibited AhR decline induced by CAPs. These preclinical…
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