Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In male Sprague-Dawley rats, rIP1, RIP3, MLKL, PGAM5 and Drp1 were expressed at high levels in the IR group, and their expression was significantly decreased in the HCH group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn MHY1485, an mTOR activator, abolished the protective effects of hydrogen in vitro, hydrogen treatment decreased the ratio of p-mTOR/mTOR and the expression of p62 and increased the…
Read ArticleThe second hypothesis is that H₂ treatment decreases sepsis-induced neuroinflammation in the hippocampus and prefrontal cortex, important areas related to short and long-term memory processing. This source-grounded publication…
Read ArticleIn The cells were resuspended in DMEM supplemented with 10% (v/v) FBS, 1% (v/v) penicillin and streptomycin to adjust the cell density to 1.5×10 6 /ml, H₂ alleviated…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Meanwhile, combination therapy with H₂ (2%) and hyperoxia (98%) increases the 14-day survival rate of moderate sepsis mice to 100%…
Read ArticleIn an animal model, the incidence of bacterial translocation at 24 h after CLP as assessed by cultivation of mesenteric lymph nodes and blood was significantly decreased in…
Read ArticleIn mice, therapy with 2% H₂ increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels but increased HO-1 levels in WT…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. In the present study, the researchers found that H₂ inhalation starting at 1 and 6 h after cecal ligation and…
Read ArticleIn vitro assays showed that burn serum reduced fibroblast proliferation and increased apoptosis (P < 0.01), which hydrogen gas mitigated by rescuing cell viability and reducing apoptosis (P…
Read ArticleIn this case report, adjunctive hydrogen inhalation was followed by temporary clinical stabilization and longitudinal immune changes in a 49-year-old man with refractory septic shock. The report described…
Read ArticleIn Animal models of SAE were generated by cecal ligation and puncture, and the SAE model was established by in vitro LPS stimulation, finally, hydrogen treatment improved the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen is a new type of antioxidant with strong free radical scavenging ability, which has been demonstrated to be…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen-based reducing atmosphere packaging (H₂-RAP), which diverges from conventional modified atmosphere packaging (MAP) that passively suppresses spoilage through CO₂, O₂,…
Read ArticleIn BACKGROUND/AIM: Rhupus syndrome, an overlap of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), is a rare condition characterized by heterogeneous clinical manifestations and difficul, this case…
Read ArticleIn a laboratory model, on day 3 of ischemia/reperfusion, the number of neurons undergoing apoptosis in the cortex was significantly lower in the H₂-rich saline group than in…
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