Pharmacokinetics of a single inhalation of hydrogen gas in pigs.

This animal study examined Pharmacokinetics of a single inhalation of hydrogen gas in pigs. The abstract describes Animal model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity

This animal study examined Biological safety of neutral-pH hydrogen-enriched electrolyzed water upon mutagenicity, genotoxicity and subchronic oral toxicity. The abstract describes Rat model; reported duration 28 days. The abstract reports: Hydrogen-dissolved water has been suggested to be effective for alleviating the oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium (HRCC) capsules in patients with metabolic syndrome: a prospective case series study.

This case report or case series examined Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium (HRCC) capsules in patients with metabolic syndrome: a prospective case series study. The abstract describes Human participants. The abstract reports: This study is the first human clinical trial evaluating HRCC capsules in patients with metabolic syndrome. Based on the safety and potential TG-lowering effects…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A Systematic Review of Molecular Hydrogen Therapy in Cancer Management.

This systematic review examined A Systematic Review of Molecular Hydrogen Therapy in Cancer Management. The abstract describes Published literature review. The abstract reports: From our analysis, H2 plays a promising therapeutic role as an independent therapy as well as an adjuvant in combination therapy, resulting in an…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Can molecular hydrogen supplementation enhance physical performance in healthy adults? A systematic review and meta-analysis.

This meta-analysis examined Can molecular hydrogen supplementation enhance physical performance in healthy adults? A systematic review and meta-analysis. The abstract describes Published literature review; sample size 597. The abstract reports: These findings suggest that H supplementation is favorable in healthy adults to improve lower limb explosive power, alleviate fatigue, and boost BLA clearance, but…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of molecular hydrogen supplementation on fatigue and aerobic capacity in healthy adults: A systematic review and meta-analysis.

This meta-analysis examined Effects of molecular hydrogen supplementation on fatigue and aerobic capacity in healthy adults: A systematic review and meta-analysis. The abstract describes Published literature review; sample size 402. The abstract reports: This meta-analysis provides moderate evidence that H supplementation alleviates fatigue but does not enhance aerobic capacity in healthy adults. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.

This animal study examined Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model. The abstract describes Canine model; reported duration 4 hours. The abstract reports: Our results demonstrated that the H-rich preservation solution attenuated ischemia-reperfusion injury in a canine left LTx model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial

This registered clinical trial examined Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial. The abstract describes Planned or registered research population. The abstract reports: The trial demonstrated that hydrogen/oxygen therapy is superior to oxygen therapy in patient with AECOPD with acceptable safety and tolerability profile. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.

This uncontrolled human study examined Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. The abstract describes Human participants. The abstract reports: The results indicated that 2% H gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.

This animal study examined High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice. The abstract describes Mouse model. The abstract reports: HCH can effectively alleviate LPS-induced ALI, which may be related to activation of Nrf2 signaling pathway and inhibition of inflammatory response and cell apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.

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APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.

This animal study examined APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis. The abstract describes Mouse model. The abstract reports: Animal experiments helped validate these results. This is an automated editorial draft based on the abstract and requires source review before publication.

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A narrative review of hydrogen therapy for COPD: aging-related insights.

This narrative review examined A narrative review of hydrogen therapy for COPD: aging-related insights. The abstract describes Published literature review. The abstract reports: H therapy shows consistent antioxidative, anti-inflammatory, and anti-senescence effects across preclinical and clinical settings, suggesting potential as an adjunctive treatment for COPD in aging…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices.

This uncontrolled human study examined A case of lung injury due to a hydrogen explosion caused by the simultaneous use of two home folk remedies devices. The abstract describes Human participants. The abstract reports: Arterial blood gas analysis showed no deterioration, and computed tomography revealed no worsening of pulmonary findings or oxygen demand. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen is a promising therapeutic agent for pulmonary disease.

This narrative review examined Molecular hydrogen is a promising therapeutic agent for pulmonary disease. The abstract describes Published literature review. The abstract reports: Short- or long-term exposure to these harmful substances often results in lung injury, causing respiratory and lung diseases. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis

This animal study examined Molecular hydrogen alleviates asthma through inhibiting IL-33/ILC2 axis. The abstract describes Mouse model. The abstract reports: These data demonstrated that H is efficient in suppressing allergen-induced asthma and could be developed as a therapeutics for asthma and other conditions of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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