Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells

This animal study examined Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells. The abstract describes Mouse model. The abstract reports: Our prospective observational study revealed that maternal production of H is significantly lower in pregnant women with PTB, suggesting its potential as a biomarker…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice.

This animal study examined Nephroprotective effect of electrolyzed reduced water against cisplatin-induced kidney toxicity and oxidative damage in mice. The abstract describes Mouse model; reported duration 28 days. The abstract reports: ERW exhibits potent nephroprotective effects on cisplatin-induced kidney damage in mice, likely due to both the increase in antioxidant-defense system activity and the inhibition…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats.

This animal study examined Protective effect of inhalation of hydrogen gas on radiation-induced dermatitis and skin injury in rats. The abstract describes Rat model. The abstract reports: Staining with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) and 8-hydroxy-2(')-deoxyguanosine (8-OHdG) showed that the proportion of apoptotic keratinocytes and the level of staining…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen and radiation protection

This randomized controlled trial examined Molecular hydrogen and radiation protection. The abstract describes Human participants. The abstract reports: A randomised, placebo-controlled investigation also showed consumption of H(2) can improve the quality of life of patients treated with radiotherapy for liver tumours. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation.

This in vitro or cellular study examined Molecular hydrogen protects human lymphocyte AHH-1 cells against 12C6+ heavy ion radiation. The abstract describes Lymphocyte cell model. The abstract reports: In conclusion, these data showed that H(2) attenuated (12)C(6+) radiation-induced cell apoptosis through reducing the ROS level and modulating apoptotic molecules, thus indicating the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.

This animal study examined Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress. The abstract describes Mouse model. The abstract reports: Within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota.

This animal study examined Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota. The abstract describes Mouse model. The abstract reports: In the present study, we found that oral gavage with hydrogen-water increased the survival rate and body weight of mice exposed to total abdominal…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects auditory hair cells from cisplatin-induced free radicals.

This in vitro or cellular study examined Hydrogen protects auditory hair cells from cisplatin-induced free radicals. The abstract describes Cell culture / in vitro model. The abstract reports: Additionally, hydroxyphenyl fluorescein (HPF) staining of the spiral ganglion showed that formation of hydroxyl radicals was successfully reduced in hydrogen-treated cochleae. This is an automated editorial draft based on the abstract and requires source review before publication.

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Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice.

This animal study examined Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice. The abstract describes Mouse model. The abstract reports: We found that UVB-mediated skin injury of ERW-bathing group was significantly low compared to TW control group in the early stage of experiment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes

This in vitro or cellular study examined Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. The abstract describes HaCaT keratinocyte model. The abstract reports: Our results showed that H exerted cytoprotective effects against stress induced by HO, t-BuOOH, and glyoxal. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

This animal study examined Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease. The abstract describes Rat model. The abstract reports: In conclusion, the PD animal model showed increased intestinal permeability together with hepatic inflammation correlated with altered gut microbiota. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease

This in vitro or cellular study examined Therapeutic Effects of Hydrogen in Animal Models of Parkinson’s Disease. The abstract describes Cell culture / in vitro model. The abstract reports: Thus, it is strongly suggested that hydrogen might provide a great advantage to prevent or minimize the onset and progression of PD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial

This randomized controlled trial examined Pilot study of H2 therapy in Parkinson’s disease: A randomized double‐blind placebo‐controlled trial. The abstract describes Human participants; sample size 9; reported duration 48 weeks. The abstract reports: The results indicated that drinking H₂-water was safe and well tolerated, and a significant improvement in total UPDRS scores for patients in the H₂-water…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease.

This animal study examined Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. The abstract describes Mouse model. The abstract reports: The concentration-dependency of H(2) showed that H(2) as low as 0.08 ppm had almost the same effect as saturated H(2) water (1.5 ppm). This is an automated editorial draft based on the abstract and requires source review before publication.

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Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases.

This narrative review examined Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases. The abstract describes Published literature review. The abstract reports: While preclinical studies demonstrate promising results, clinical trials conducted thus far have yielded mixed outcomes, with some trials reporting limited or no therapeutic benefit. This is an automated editorial draft based on the abstract and requires source review before publication.

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