Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In cultured tumor cells, hydrogen-rich water combined with platinum colloid showed greater antitumor activity than hydrogen-rich water alone and was associated with apoptosis-like cell changes. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed…
Read ArticleThis narrative review examined the available evidence on molecular hydrogen. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and…
Read ArticleIn mice, the present study showed that hydrogen gas therapy increased the 7-day survival rate, improved cognitive function, increased the mitochondrial function (MMP, ATP level, complex I activity)…
Read ArticleThis study evaluated a functional eye dressing designed to deliver both molecular hydrogen and oxygen around the eye. In uncontrolled clinical observations involving 28 patients, the authors reported…
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleHydrogen improved microvascular endothelial-cell viability partly through PI3K/Akt/GSK3β activation and inhibition of autophagy in a traumatic-brain-injury model. These findings come from a laboratory model and suggest molecular hydrogen's…
Read ArticlePrevious clinical studies revealed that electrolyzed hydrogen water (EHW) is effective to reduce oxidative stress during hemodialysis in patients with chronic dialysis. This source-grounded publication contributes evidence relevant…
Read ArticleIn Neuronal degeneration within hippocampal Cornu Ammonis 1 (CA1) regions was examined by Fluoro-Jade staining ex vivo, both hydrogen gas treatment regimens significantly improved spatial learning function and…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen (H₂) is colorless, odorless, and the lightest of gas molecules. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn a laboratory model, H₂ treatment decreased the levels of oxidative products (malondialdehyde and 8-iso-prostaglandin F2α) and increased the activities of endogenous antioxidant enzymes (superoxide dismutase and catalase)…
Read ArticleThis publication is a scientific hypothesis or perspective about molecular hydrogen and identifies directions for further research.
Read ArticleIn exploring the underlying mechanisms, the researchers found that hydrogen could markedly mitigate the degree of IR-induced ER stress and apoptosis (P < 0.05). These preclinical findings add…
Read ArticleHydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage Compared to cells pretreated without hydrogen, the researchers demonstrated that treating cells with hydrogen-rich PBS before irradiation…
Read ArticleIn vitro, LPS treatment increased the expression levels of STIM1 and Orai1 in PMVECs, while H₂ reversed these changes. The authors concluded that the present study suggested that…
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Molecular hydrogen kidney health…
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