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In rats, the data showed that the spatial recognition memory and fear memory of the rats treated with sevoflurane decreased compared with the control, and the cognitive function of the rats treated with sevoflurane and hydrogen gas significantly increased in comparison with…
Read ArticleIn rats, HRW intake mainly induced significant increase in the abundance of Lactobacillus, Ruminococcus, Clostridium XI, and decrease in Bacteroides. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, both inhaling 2% hydrogen and ischemic postconditioning treatment reduced the ischemic size and serum troponin I level in rats with I/R injury, and inhaling hydrogen showed…
Read ArticleIn rats, the eAE-hydrogen-rich saline increased significantly left ventricular systolic pressure, reduced left ventricular end-diastolic pressure, and potentiated + dp/dtmax, -dp/dtmax, heart coefficient and pH after MI injury.…
Read ArticleIn rats, the LPS challenge reduced the expression of genes related to FAO, including perioxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), perioxisome proliferator-activated receptor alpha (PPARα), Estrogen-related receptor…
Read ArticleIn JAK2 knockdown experiments using siRNA, HRS treatment following hypoxia/reoxygenation also significantly increased the viability of myocardial cells, decreased the rate of myocardial cellular apoptosis, elevated the levels…
Read ArticleIn rats, delayed resuscitation for scalded rats with hydrogen-rich saline is helpful in the recovery of systolic pressure, and it can ameliorate lung tissue injury caused by reperfusion…
Read ArticleIn an animal model, hydrogen significantly alleviated brain tissue histological damage, promoted HO-1 expression, upregulated levels of SOD, and decreased the levels of MDA in brain tissue after…
Read ArticleIn mice, significant lung injury at 24 h post-TBI got significantly reduced by treatment of 2% H₂. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read ArticleIn mice, mGNs demonstrated superior neuroprotection compared with hydrogen inhalation and showed favorable biosafety profiles. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn this asphyxial CA rat model, the improved postresuscitation EEG characteristics for animals treated with hydrogen are correlated with the better 96 h neurological outcome and predicted survival.…
Read ArticleIn Wistar rats, serum levels of endotoxin, syndecan-1, malondialdehyde, and tumor necrosis factor-α decreased, whereas superoxide dismutase levels increased, indicating that inhalation of 2% hydrogen attenuated the damage…
Read ArticleIn rats, hydrogen saline significantly reduced the infarct volume and edema and improved the neurological function, when it was administered at 0, 3 and 6 h after reperfusion.…
Read ArticleIn contrast, hydrogen gas may have increased survival of animals that would have died without treatment, thus biasing the neurobehavior scores of the SAH + hydrogen group toward…
Read ArticleIn rats, hydrogen gas reduced brain swelling, improved neurological function, and lowered markers of oxidative stress and neuronal pyroptosis after subarachnoid hemorrhage. These preclinical findings add evidence supporting…
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