Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In female C57BL/6 rats, the group that received H₂-rich saline treatment showed a significant increased in SOD activities compared to the untreated irradiated group (51.81±5.67 vs 33.48±4.28, P < 0.05). Nitrogen-rich saline treatment did not reduce oxidative stress or the inflammatory response…
Read ArticleIn rats, it has previously been demonstrated that hydrogen gas selectively reduces cytotoxic ROS such as the hydroxyl radical [ 11, 16 ]. These preclinical findings add evidence…
Read ArticleIn rats, hydrogen significantly reduced the severity of dermatitis, accelerated tissue recovery, and reduced the extent of radiation-induced weight loss in rats after a single dose of 15…
Read ArticleIn rats, treatment with molecular hydrogen-rich water (HRW) reduced these values to the level of non-irradiated controls. miRNA-1 is known to be involved in cardiac hypertrophy, and was…
Read ArticleIn mice, within 1 wk after whole thorax irradiation, immunohistochemistry and immunoblotting showed that H(2) treatment reduced oxidative stress and apoptosis, measures of acute damage, in the lungs…
Read ArticleIn rats, the healing time was shortened in the two HRW-treated groups (P < 0.05). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn mice, after exposure to 15 Gy TAI, the animal survival rate was decreased by 50% in the control vehicle group, but it was decreased by only 10%…
Read ArticleIn mice, further, the level of interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-12p70 in ERW group decreased whereas those of IL-10 increased. These preclinical findings add evidence…
Read ArticleIn guinea pigs, post-hoc analysis showed that the threshold shift differed significantly ( p < 0.05) between different frequencies in the Cispt group but not the Cispt+H₂ group…
Read ArticleIn female Sprague Dawley rats, hydrogen-rich saline attenuated the FSH release, elevated the level of E2, improved the development of follicles, and reduced the damage to the ovarian…
Read ArticleIn an animal model, particularly, hydrogen-rich water showed a promising reduction in these symptoms. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn male Sprague Dawley rats, pET/CT imaging showed increased hippocampal glucose uptake in the IR group, which was alleviated by HRW treatment. These preclinical findings add evidence supporting…
Read ArticleIn rats, increased gut permeability, measured by FITC-dextran assay, was detected in PERM group compared to control and PERM+ERW groups. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, methamphetamine-induced behavioral analysis showed that molecular hydrogen prevented both the development and progression of the nigrostrital degeneration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice treated with H₂ water, the loss of dopaminergic neurons in SNpc was about a half of that in mice drinking non-H₂ water (54% of saline &…
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