Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.
This animal study examined Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: The histological study demonstrated milder inflammation in the DSS + HRW group, which was similar to normal inflammatory levels, and the macroscopic and microcosmic…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.
This animal study examined Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study
This animal study examined Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Although critically ill conditions can trigger NOMI, the model used in this study did not involve transmural necrosis. Under such conditions, hydrogen inhalation therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice.
This animal study examined A preliminary therapeutic study of the effects of molecular hydrogen on intestinal dysbiosis and small intestinal injury in high-fat diet-loaded senescence-accelerated mice. The abstract describes Mouse model; sample size 10. The abstract reports: Our findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.
This animal study examined Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.
This animal study examined Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.
This uncontrolled human study examined Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis. The abstract describes Human participants. The abstract reports: The results revealed significant reductions in inflammation and oxidative stress both in vitro and in vivo. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
This animal study examined Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Sirt1 mediates light-induced damage mitigation by HRS through inhibition of apoptosis and oxidant-stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
This animal study examined The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Oxidative stress has been identified as one of the contributing mechanisms of spaceflight-associated neuro-ocular syndrome (SANS), and hydrogen (H) has demonstrated significant antioxidant and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway.
This animal study examined Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that administration of HPC significantly inhibited the apoptosis of RGCs and protected the visual function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice.
This animal study examined Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Given the known contributions of oxidative stress caused by reactive oxygen species (ROS) and selective inhibition of potent ROS peroxynitrite and OH·by H gas…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.
This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAn Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress
Corneal alkali burns are potentially blinding injuries. Alkali induces oxidative stress in corneas followed by excessive corneal inflammation, neovascularization, and untransparent scar formation. Molecular hydrogen (H), a potent reactive oxygen species (ROS) scavenger, suppresses oxidative stress and enables corneal healing when applied on the corneal surface.
Read MoreProtective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression
This animal study examined Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Our findings demonstrate that inhalation of hydrogen gas could alleviate retinal oedema, shorten reopen time and improve retinal function, and the potential mechanism might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.
This in vitro or cellular study examined Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: This result likely occurs by inhibiting the activation of glial cells, decreasing the production of the iNOS and GRP78 and promoting glutamate clearance. This is an automated editorial draft based on the abstract and requires source review before publication.
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