Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In female BALB/c mice, there were no significant differences in dissolved hydrogen concentrations between 5 mg/mL and 10 mg/mL CCH solutions. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn the HRW dressing groups (DH2 and non-DH2), the wound closure rate increased numerically compared to the other groups, and wound healing occurred earlier than the other groups…
Read ArticleIn SH‑SY5Y cells, H₂ improved cell viability and MMP, and reduced apoptosis and ferroptosis following OGD/R. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn an animal model, the decrease in reperfusion damage improved long term neurological function, such as thermoregulation and weight maintenance, at one week, implying that hydrogen gas can…
Read ArticleIn mice, the authors' cognition results showed that 7 days exposure to H₂ gas improved learning by 62% in time compared to STZ animals in room air. These…
Read ArticleIn an animal model, anticipate that this bacterial therapy for photosynthetic H₂ production could provide an improved treatment for I/R-related diseases. These preclinical findings add evidence supporting molecular…
Read ArticleIn mice, mice coadministered of hydrogen gas with sevoflurane did not exhibit the deficits of maternal behaviors. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and…
Read ArticleIn ICR mice with lipopolysaccharide-induced inflammation-related behavioral changes, however, therapy with H₂ increased the survival rate and alleviated the severity of lung injury, reduced the HMGB1 level, and…
Read ArticleIn mice, H₂ therapy in the animals with severe sepsis was associated with reduced intestinal injury, decreased numbers of colony-forming unit and apoptotic cells, reduced levels of biochemical…
Read ArticleIn male C57BL/6 mice, lung HE staining showed that there were obvious lung injuries in the sepsis group which were alleviated in the H₂ treatment group. These preclinical…
Read ArticleIn mice, hydrogen increased Nrf2 expression and inhibited the SAE-induced expression of NLRP3, caspase-1, cytokines IL-1β and IL-18, neuronal apoptosis, and mitochondrial dysfunction in WT mice but not…
Read ArticleIn an animal model, from what has been discussed above, this injectable spontaneous H₂-releasing hydrogel is promising for OA treatment. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, as a result, Mg@PLPE MSs treated IVDD rats exhibit minimal nucleus pulposus decrease, less extracellular matrix degradation, minimal radial fissure of fibrous rings, and higher disc…
Read ArticleIn female Sprague-Dawley rats, inhaled H₂ improved hemodynamics and right heart function, reversed right ventricular hypertrophy, and prevented pulmonary vessel reconstitution in both prevention and treatment approaches. These…
Read ArticleIn mice, herein, the researchers report artificial nanoreactors that mimic natural photosynthesis to realize near-infrared (NIR) light-driven photocatalytic H₂ evolution in situ. These preclinical findings add evidence about…
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