Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, 3 G, preincubation of cells with ASp@BS under dark conditions led to a reduction in intracellular ROS, indicating that ASp@BS can effectively defend against oxidative stress by generating H₂. Crucially, in contrast to conventional immunosuppressive agents, which are associated with…
Read ArticleIn mice, the hydrolysis of CSNs produces anti-oxidative H₂, alkaline Ca(OH)2, and silica. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological…
Read ArticleIn mice, this porous microsphere scaffold is implanted into bone defects to achieve the sustained release of hydrogen gas, magnesium ions (Mg2+), and dimethyl fumarate (DMF). These preclinical…
Read ArticleIn diabetic murine models, this approach accelerated wound closure, enhanced neovascularization, and reduced inflammatory infiltration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn rats, the H₂ group preserved ERK expression, whereas the CTRL and H₂ + 3-MA groups showed remarkably reduced ERK expression. *: statistical significance with p < 0.001…
Read ArticleIn fact, oral administration of the Si-based agent to mice has been shown to increase hydrogen concentration in the intestine. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleIn mice, to address these limitations, a partially reduced zinc-doped zeolitic imidazolate framework-8 (ReZIF-8) is developed, functioning as a dual-functional nanoplatform for both intracellular hydrogen generation and controlled…
Read ArticleIn mice, H₂ treatment significantly ameliorated intestinal injury, reduced epithelial barrier leakage (evidenced by decreased serum DAO and FITC-dextran), and suppressed systemic inflammation. scRNA-seq revealed that H₂ restored…
Read ArticleIn mice, although hydrogen gas (H₂) exhibits promising neuroprotective potential, conventional H₂ therapy is severely limited by unstable and transient H₂ release, failing to sustain long-term treatment requirements…
Read ArticleIn rats, injection of HS attenuated morphine tolerance in a dose-dependent manner, decreased proinflammatory cytokine expression, inhibited astrocyte activation, decreased GLT-1 and GS nitration, and inhibited membrane trafficking…
Read ArticleIn an animal model, compared with traditional electrolyzed water methods, this direct dissolution system delivers substantially higher and more stable H₂ concentrations. These preclinical findings add evidence supporting…
Read ArticleIn mice, after 7 days, DSS-induced loss of body weight, increase of colitis score, shortening of colon length, pathological changes and elevated levels of TNF-α, IL-1β, MDA, and…
Read ArticleIn rats, compared with the control group, preservation in H₂-rich HTK significantly enhanced the percentage recovery of hemodynamic parameters, which was parallel to the diminished re-beating time and…
Read ArticleIn rats, rBC and Hb values as well as the activity of SOD and GSH-PX were reduced after administration of linoleic acid, which was ameliorated by treatment with…
Read ArticleIn an animal model, among the seven representative bacteria that the researchers analyzed for hydrogen production, three bacterial groups/genera/species ( Blautia coccoides group, Clostridium leptum subgroup, and Bacteroides…
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