Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, molecular hydrogen improved the weight, survival and long-term neurological function of rats with diabetic stroke and alleviated changes in blood glucose levels before and after middle cerebral artery occlusion (MCAO), but no difference in circadian rhythm was observed. These preclinical…
Read ArticleIn mice, H₂ could promote very early M1-to-M2 polarization (on days 2-3 post wounding, 2-3 days earlier than in conventional wound healing), without disturbing the functions of the…
Read ArticleIn this rat model cardiac arrest and CPR, gender did not affect resuscitation but associated with neurological outcome. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes,…
Read ArticleIn rats, the hydrogen concentration in the heart, liver, and spleen showed an increasing trend over time, and all exhibited a significant increase in hydrogen concentration at 5…
Read ArticleIn mice, the excellent small-sized therapeutic nanoparticles the researchers designed and synthesised can easily cross the blood-brain barrier to the site of inflammation in the brain and achieve…
Read ArticleIn mice, si-based agents are effective against allergic bronchial asthma and may serve as superior materials for hydrogen therapy. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn mice, hydrogen gas treatment increased the 7-d survival rate of severe CLP mice to 60 % (Compared with severe sepsis group, P <0.05) and significantly reduced the…
Read ArticleThese preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleThe researchers observed significant dilatation and higher Z scores in the left coronary artery (LCA) in D21 and D28 in mice after LCWE treatment compared to the control…
Read ArticleIn mice, hydrogen inhalation attenuated the immune response; decreased the levels of IL-4, IL-5 and IL-13; and further increased the mRNA expression levels of Treg-associated cytokines, namely, IL-10…
Read ArticleIn an animal model, although lung neutrophil counts were significantly higher in the HI-H₂ group, pulmonary gas exchange remained preserved, with no significant differences in arterial blood gases,…
Read ArticleIn an animal model, bacteria in the large intestinal can produce endogenous hydrogen, and the authors' preliminary experiments revealed that oral administration of mannitol in humans and animals…
Read ArticleIn rats, hydrogen-rich saline reversed these changes and relieved morphological renal injury and I/R-induced apoptosis, while no significant changes were observed in the nitrogen-rich saline-treated group compared with…
Read ArticleIn guinea pigs, hydrogen-rich saline can alleviate experimental noise-induced hearing loss in guinea pigs, partially by preventing the death of cochlear hair cells after intensive noise exposure. These…
Read ArticleIn rats, eliminating peroxynitrite with hydrogen-rich saline protected against hyperalgesia and attenuated DMT1(-)IRE overexpression and iron accumulation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…
Read Article