Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats
This animal study examined Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats. The abstract describes Rat model. The abstract reports: Experimental results showed that a 7-day MSN intervention significantly attenuated anxiety-like behaviors while reversing the synaptic deficits induced by SPS&S in prefrontal cortical regions. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation.
This animal study examined Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrate that HS restored behavioral deficits after HI in neonatal mice. These beneficial effects, in part, involve promoting microglia M2 polarization and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
This animal study examined Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: We found that HRS administration was able to inhibit the acquisition and transfer of 0.1 and 0.5 mg/kg METH-induced behavioral sensitization to a certain extent,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
This randomized controlled trial examined Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: In healthy individuals, aging, job stress, and cognitive load over several hours also induce increases in oxidative stress, suggesting that preventing the accumulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water on depressive-like behavior in mice.
This uncontrolled human study examined Effects of hydrogen-rich water on depressive-like behavior in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: Emerging evidence suggests that neuroinflammation and oxidative stress may be major contributors to major depressive disorder (MDD). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdministration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model
This animal study examined Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. The abstract describes Mouse model. The abstract reports: We have previously demonstrated in the MIA mouse model that maternal administration of H attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring.
This animal study examined Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Due to its anti-inflammatory and anti-oxidative effects, recent research has demonstrated that molecular hydrogen can serve as a new medical approach for depression, anxiety…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdditive effect of clove essential oil combined with hydrogen inhalation improves psychological harm caused by lipopolysaccharide in mice.
This animal study examined Additive effect of clove essential oil combined with hydrogen inhalation improves psychological harm caused by lipopolysaccharide in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Our results suggest that a combination of CEO and H has the potential to treat psychological disorders or neuropsychiatric disorders. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
This animal study examined Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 3 days. The abstract reports: We found that HRS administration significantly reduced body weight loss, jumping behavior and wet-dog shakes in mice underwent naloxone-precipitated withdrawal, and attenuated anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
This animal study examined Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder. The abstract describes Animal model. The abstract reports: Our results showed that increased SDS and SAS indices and decreased alpha diversity indicated more serious mental disorders and lower bacterial diversity in METH…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway.
This animal study examined Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The result showed that HS administration alleviated HI-induced edema, infract volume and cellular apoptosis within the cortex of neonatal mice. Accompanying these indices of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
This animal study examined Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The potential use of molecular hydrogen (H) as a new therapy for neurological disorders has been demonstrated. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats
This animal study examined Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
This animal study examined Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 3 days. The abstract reports: These results indicate the therapeutic potential of HW in preventing acute injury of the liver with attenuation of an increase in oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression
This animal study examined Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression. The abstract describes Mouse model. The abstract reports: The MCDHF I/R group showed higher levels of AST and ALT in serum, TUNEL-positive apoptotic cells, F4/80 immunopositive cells, mRNA levels of inflammatory cytokines,…. This is an automated editorial draft based on the abstract and requires source review before publication.
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