Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse

This animal study examined Taurine, Coenzyme Q10, and Hydrogen Water Prevents Germanium Dioxide-Induced Mitochondrial Dysfunction and Associated Sensorineural Hearing Loss in mouse. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the current study, we showed that supplementation with germanium dioxide (GeO) in CBA/J mice resulted in SNHL due to the degeneration of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence.

This animal study examined A link between gut community metabolism and pathogenesis: molecular hydrogen-stimulated glucarate catabolism aids Salmonella virulence. The abstract describes Mouse model. The abstract reports: Our results link a gut microbiome-produced diffusible metabolite to augmenting bacterial pathogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.

This animal study examined Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism. The abstract describes Mouse model. The abstract reports: The expression of might be regulated indirectly through sequential regulation by H, 4-hydroxy-2-nonenal, and Akt/FoxO1 signaling, as suggested in cultured cell experiments. This is an automated editorial draft based on the abstract and requires source review before publication.

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Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions.

This narrative review examined Mitochondria: one of the vital hubs for molecular hydrogen’s biological functions. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats.

This animal study examined Hydrogen-rich saline attenuates neuronal ischemia–reperfusion injury by protecting mitochondrial function in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen, a popular antioxidant gas, can selectively reduce cytotoxic oxygen radicals and has been found to protect against ischemia-reperfusion (I/R) injury of multiple organs. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice.

This animal study examined Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline. The abstract reports: Previous studies have demonstrated that hydrogen-rich saline (HS) protects against bile duct ligation (BDL)-induced liver injury by suppressing oxidative stress and inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential.

This in vitro or cellular study examined Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduced mitochondrial membrane potential. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial

This randomized controlled trial examined Hydrogen Activates ATP-Binding Cassette Transporter A1-Dependent Efflux Ex Vivo and Improves High-Density Lipoprotein Function in Patients With Hypercholesterolemia: A Double-Blinded, Randomized, and Placebo-Controlled Trial. The abstract describes Human participants; sample size 34; reported duration 10 weeks. The abstract reports: H2 activates ATP-binding cassette transporter A1-dependent efflux, enhances HDL antiatherosclerotic functions, and has beneficial lipid-lowering effects. The present findings highlight the potential role of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response.

This animal study examined Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. The abstract describes Mouse model. The abstract reports: We found that H activated the expression of sets of genes regulated by histone H3K27 methylation status. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water affected blood alkalinity in physically active men.

This randomized controlled trial examined Hydrogen-rich water affected blood alkalinity in physically active men. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 14 days. The abstract reports: These results support the hypothesis that HRW administration is safe and may have an alkalizing effect in young physically active men. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study.

This randomized controlled trial examined Molecular hydrogen inhalation modulates resting metabolism in healthy females: findings from a randomized, double-blind, placebo-controlled crossover study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 60 minutes. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.

This animal study examined Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results collectively indicated that hydrogen significantly attenuated CUMS-induced depressive-like behavior and monoamine neurotransmitter deficiency, as well as protected the brain from oxidative stress…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids.

This animal study examined Hydrogen-rich water supplementation improves metabolic profile during peripartum period in Gurcu goats and enhances the health and survival of kids. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.

This animal study examined Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice. The abstract describes Mouse model. The abstract reports: Although the underlying mechanisms of bmTBI are largely unknown, some studies suggested that bmTBI is associated with blood-brain barrier disruption, oxidative stress, and edema…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside.

This narrative review examined Therapeutic Potential of Molecular Hydrogen in Metabolic Diseases from Bench to Bedside. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.

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