Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress
This animal study examined Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS may play a protective role in attenuating allergic inflammation, and suppressing the increase and activation of eosinophils in AR possibly through antioxidation effect…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
This uncontrolled human study examined Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. The abstract describes Human participants; reported duration 60 min. The abstract reports: Recently, it has been suggested that hydrogen gas (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical (•OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives.
This narrative review examined Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives. The abstract describes Published literature review. The abstract reports: This situation results in impaired gas exchange, hypoxia, and other sequelae that lead to multisystem organ failure and death. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIn Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation.
This animal study examined In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation. The abstract describes Mouse model. The abstract reports: Experimental results indicate that the Lip NR system that can photosynthesize H gas has great potential for mitigating oxidative stress in tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
This in vitro or cellular study examined Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators. The abstract describes Cell culture / in vitro model. The abstract reports: We previously showed that H2 acts as a novel antioxidant to protect cells against oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model
This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
This animal study examined Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHeme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.
This in vitro or cellular study examined Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen exerts a regulating role in the release of pro- and anti-inflammatory cytokines in LPS-stimulated macrophages, and this effect is at least partly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation.
This animal study examined Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
This uncontrolled human study examined Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses.
This animal study examined Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Mice that consumed HRW for ≥P4 weeks ran significantly longer distances, showed less muscle fatigue, and had lower levels of markers of oxidative stress,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.
This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum.
This uncontrolled human study examined Hydrogen-rich bath with nano-sized bubbles improves antioxidant capacity based on oxygen radical absorbing and inflammation levels in human serum. The abstract describes Human participants; hydrogen delivered as hydrogen bath. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of Hydrogen-Rich Water on Growth, Redox Homeostasis and Hormonal, Histological and Immune Systems in Rats Exposed to High Cage Density Stress.
This animal study examined Effects of Hydrogen-Rich Water on Growth, Redox Homeostasis and Hormonal, Histological and Immune Systems in Rats Exposed to High Cage Density Stress. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 3 months. The abstract reports: The stress-related physiological parameters were reduced in the HRW + stress group compared to the stress group. HRW could be suggested when the organism is found…. This is an automated editorial draft based on the abstract and requires source review before publication.
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