Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention

This animal study examined Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.

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1.2% Hydrogen gas inhalation protects the endothelial glycocalyx during hemorrhagic shock: a prospective laboratory study in rats

This animal study examined 1.2% Hydrogen gas inhalation protects the endothelial glycocalyx during hemorrhagic shock: a prospective laboratory study in rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 1.2% H gas protected the endothelial glycocalyx and prolonged survival time during hemorrhagic shock. Therapeutic efficacy might vary depending on the concentration. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways.

This animal study examined Hydrogen (H) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways. The abstract describes Mouse model; reported duration 7 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth.

This uncontrolled human study examined Magnesium galvanic cells produce hydrogen and modulate the tumor microenvironment to inhibit cancer growth. The abstract describes Human participants. The abstract reports: Our research suggests that the galvanic cells for hydrogen therapy based on implantable metals may be a safe and effective cancer treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas activates coenzyme Q10 to restore exhausted CD8 T cells, especially PD-1Tim3terminal CD8 T cells, leading to better nivolumab outcomes in patients with lung cancer.

This uncontrolled human study examined Hydrogen gas activates coenzyme Q10 to restore exhausted CD8 T cells, especially PD-1Tim3terminal CD8 T cells, leading to better nivolumab outcomes in patients with lung cancer. The abstract describes Human participants; sample size 14. The abstract reports: In multivariate analysis, PD-1Tim-3terminal CD8 T cells (PDT+) were an independent poor prognostic factor in OS, and CoQ10 showed a tendency to be associated…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas in Cancer Treatment

This narrative review examined Aug 2019 (cancer, review)Frontiers | Hydrogen Gas in Cancer Treatment | Oncology. The abstract describes Published literature review. The abstract reports: Growing evidence has shown that hydrogen gas can either alleviate the side effects caused by conventional chemotherapeutics, or suppress the growth of cancer cells…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

This animal study examined Engineering a Tumor‐Targeted MgH 2 @Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report.

This case report or case series examined Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report. The abstract describes hydrogen delivered as hydrogen inhalation; reported duration 28 months. This is an automated editorial draft based on the abstract and requires source review before publication.

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Electrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy

This in vitro or cellular study examined Electrolyzed Hydrogen Water Improves Chemosensitivity to Anticancer Drugs by Potently Suppressing Autophagy. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Acid‐Responsive H2‐Releasing 2D MgB2 Nanosheet for Therapeutic Synergy and Side Effect Attenuation of Gastric Cancer Chemotherapy

This in vitro or cellular study examined Acid‐Responsive H2‐Releasing 2D MgB2 Nanosheet for Therapeutic Synergy and Side Effect Attenuation of Gastric Cancer Chemotherapy. The abstract describes Stem-cell model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway.

This uncontrolled human study examined Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway. The abstract describes Human participants. The abstract reports: This study demonstrates that high concentrations of H exert an inhibitory effect on CRC by inhibiting the pAKT/SCD1 pathway. Further studies are warranted for…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption.

This in vitro or cellular study examined Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption. The abstract describes Lymphocyte cell model; hydrogen delivered as hydrogen inhalation. The abstract reports: These results support a mechanism by which the H resulting from inulin fermentation by the GM diffuses across the intestinal barrier and stimulates the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification.

This animal study examined The Preventive Role of Hydrogen-Rich Water in Thioacetamide-Induced Cholangiofibrosis in Rat Assessed by Automated Histological Classification. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: RNA-seq analysis revealed that H results in a decline in glycolysis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of Hydrogen Inhalation Therapy on Hearing Loss of Patients With Nasopharyngeal Carcinoma After Radiotherapy.

This observational study examined Effect of Hydrogen Inhalation Therapy on Hearing Loss of Patients With Nasopharyngeal Carcinoma After Radiotherapy. The abstract describes Human participants; sample size 17; hydrogen delivered as hydrogen inhalation. The abstract reports: This is the first prospective study on the effect of hydrogen inhalation on hearing improvement in patients with deafness after radiotherapy/chemotherapy for nasopharyngeal carcinoma,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study.

This study protocol examined Protective effects of hydrogen gas inhalation on radiation-induced bone marrow damage in cancer patients: a retrospective observational study. The abstract describes Planned or registered research population; sample size 7; hydrogen delivered as hydrogen inhalation; reported duration 30 minutes. The abstract reports: The results obtained demonstrated that H gas inhalation therapy alleviated IMRT-induced bone marrow damage without compromising the anti-tumor effects of IMRT. This is an automated editorial draft based on the abstract and requires source review before publication.

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