Hydrogen: an advanced and safest gas option for cancer treatment.
This uncontrolled human study examined Hydrogen: an advanced and safest gas option for cancer treatment. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation and hydrogen-rich saline. The abstract reports: Currently available cancer treatment options, such as surgery, chemotherapy, radiation, and immunotherapy, are limited, and the results could be unsatisfactory due to systemic toxicity…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model
This animal study examined Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Administration of HRW, with or without 5-FU, may serve as a therapeutic for treating CRC. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma: a single-center, randomized controlled study.
This single-center randomized controlled trial evaluated perioperative hydrogen/oxygen inhalation in adults undergoing first-time glioma surgery. Eighty-nine patients were randomized and 75 were included in the per-protocol analysis (38 hydrogen/oxygen and 37 oxygen control). The intervention group inhaled 66.7% hydrogen and 33.3% oxygen by nasal cannula for more than 2 hours daily from admission through discharge; the control group received 33.3% oxygen. Serial CT measurements showed lower brain-edema volume and greater edema regression before discharge in the hydrogen group. Selected sleep and pain measures improved, while inflammatory markers, hospital and ICU stay, and recorded complications did not differ significantly between groups.
Read MoreControlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis.
This animal study examined Controlled release of hydrogen by implantation of magnesium induces P53-mediated tumor cells apoptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and hydrogen-rich saline. The abstract reports: We find that the localized release of hydrogen increases the expression level of P53 tumor suppressor proteins, as demonstrated by the RNA sequencing and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTwo weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study.
This uncontrolled human study examined Two weeks of hydrogen inhalation can significantly reverse adaptive and innate immune system senescence patients with advanced non-small cell lung cancer: a self-controlled study. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 4 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas represses the progression of lung cancer via down-regulating CD47.
This animal study examined Hydrogen gas represses the progression of lung cancer via down-regulating CD47. The abstract describes Mouse model. The abstract reports: In our previous study, our project group found that H2 could decrease the expression of CD47 in lung cancer A549 cells via the next-generation…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
This animal study examined Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: This study extended our original analysis of the ability of hydrogen to stimulate NLRP3 inflammasome/GSDMD activation in pyroptosis and revealed possible mechanism (s) for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSuppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis.
This in vitro or cellular study examined Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis. The abstract describes A549 cell model. The abstract reports: Our previous study found that hydrogen gas (H) could efficiently inhibit lung cancer progression; however, the underlying mechanisms still remains to be elucidated. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of oral hydrogen water as an antioxidant on pulmonary hypertension
This animal study examined Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that the mean pulmonary arterial pressure, right ventricle weight and right ventricular hypertrophy index in MCT group were significant higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension.
This animal study examined The Role of Mast Cells in the Remodeling Effects of Molecular Hydrogen on the Lung Local Tissue Microenvironment under Simulated Pulmonary Hypertension. The abstract describes Rat model. The abstract reports: MPH resulted in a significantly increased number of MCs in both the pneumatic and respiratory parts of the lungs, an increased number of tryptase-positive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation
This animal study examined Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation. The abstract describes Rat model; reported duration 5 weeks. The abstract reports: We found that the systolic and diastolic blood pressure (BP) increased significantly in rats exposed to intermittent hypoxia, both of which were markedly attenuated…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats.
This animal study examined Effects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen-rich water (HW) has been suggested to possess antioxidant properties of value in treatments of lifestyle diseases and for prevention of latent pathologies. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model.
This animal study examined Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: These results suggest that hydrogen-rich saline ameliorates the progression of pulmonary hypertension induced by monocrotaline in rats, which may be associated with its antioxidant…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats.
This animal study examined Hydrogen Inhalation Reduces Lung Inflammation and Blood Pressure in the Experimental Model of Pulmonary Hypertension in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: The results showed that, although hydrogen inhalation had no effect on the main markers of pulmonary hypertension induced by monocrotaline injection, there was a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis.
This narrative review examined Molecular hydrogen therapy in musculoskeletal conditions: An evidence-based review and critical analysis. The abstract describes Published literature review; hydrogen delivered as hydrogen water. The abstract reports: Preclinical models consistently showed reductions in reactive oxygen species, inflammatory cytokines, and improved cell viability. This is an automated editorial draft based on the abstract and requires source review before publication.
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