Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis.

This animal study examined Hydrogen inhibits the proliferation and migration of gastric cancer cells by modulating lncRNA MALAT1/miR-124-3p/EZH2 axis. The abstract describes Mouse model. The abstract reports: These data demonstrated that H might be developed as a therapeutics of gastric cancer and lncRNA MALAT1/miR-124-3p/EZH2 axis could be a target for intervention. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen as a Novel Antitumor Agent: Possible Mechanisms Underlying Gene Expression.

This narrative review examined Molecular Hydrogen as a Novel Antitumor Agent: Possible Mechanisms Underlying Gene Expression. The abstract describes Published literature review. The abstract reports: While many antitumor drugs have yielded unsatisfactory therapeutic results, drugs are one of the most prevalent therapeutic measures for the treatment of cancer. This is an automated editorial draft based on the abstract and requires source review before publication.

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A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation.

This uncontrolled human study examined A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 10 months. The abstract reports: This is the first report of pseudo-progression followed by sustained remission after hydrogen inhalation. This phenomenon is similar to the pseudo-progression-remission pattern that occurs…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response.

This in vitro or cellular study examined Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response. The abstract describes Cell culture / in vitro model. The abstract reports: We found that hydrogen enhances proliferation of four out of seven human cancer cell lines (the responders). This is an automated editorial draft based on the abstract and requires source review before publication.

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“Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients

This study protocol examined “Real world survey” of hydrogen-controlled cancer: a follow-up report of 82 advanced cancer patients. The abstract describes Planned or registered research population; sample size 82; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice.

This animal study examined Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. The abstract describes Mouse model. The abstract reports: Here in this study, we found that H(2) protects mice from radiation induced thymic lymphoma in BALB/c mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis.

This animal study examined Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: In this study, we found that intraperitoneal injection of hydrogen-rich saline (H saline) ameliorated the mortality, cardiac dysfunction, and histopathological changes caused by DOX…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.

This randomized controlled trial examined Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 6 weeks. The abstract reports: Daily consumption of hydrogen-rich water is a potentially novel, therapeutic strategy for improving QOL after radiation exposure. Consumption of hydrogen-rich water reduces the biological…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report.

This case report or case series examined Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: This is the first report of an efficacy and safety study about hydrogen therapy in patient with metastatic GBC and a critical general condition,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer.

This uncontrolled human study examined Therapeutic efficacy of hydrogen‑rich saline alone and in combination with PI3K inhibitor in non‑small cell lung cancer. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Similarly, the results of the present study demonstrated that administration of the two agents in combination may inhibit phospho‑Akt activity, and reduce expression of…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.

This randomized controlled trial examined Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy. The abstract describes Human participants; sample size 80; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer.

This animal study examined Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Furthermore, hydrogen water enhanced cell apoptosis in cancer cells, resulting in a marked increase in the expression of p-AMPK, AIF and Caspase 3 in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro

This in vitro or cellular study examined Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells in vitro. The abstract describes Epithelial cell model; hydrogen delivered as hydrogen water. The abstract reports: The results showed that KYSE-70 cells and HEEpiCs were generally inhibited by H-silica administration, and there was a significant proliferation-inhibitory effect in an H-silica…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice.

This animal study examined Molecular Hydrogen Attenuates Chronic Inflammation and Delays the Onset of Ultraviolet B-Induced Skin Carcinogenesis in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: These findings suggest that continuous H administration attenuates inflammation-associated early UVB carcinogenesis through modulation of the IL-6/STAT3 and ERK/JNK pathways, supporting its use as…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study

This randomized controlled trial examined Effects of Hydrogen Water Gargling on Oral Mucositis and Pain in Head and Neck Cancer Patients: A Randomized Controlled Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Assessments were conducted at baseline (T0) and on Days 1 (T1), 3 (T2), 7 (T3), and 14 (T4) post-treatment.ResultsThe HW group showed significant OM…. This is an automated editorial draft based on the abstract and requires source review before publication.

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