Molecular hydrogen: a therapeutic antioxidant and beyond.
This uncontrolled human study examined Molecular hydrogen: a therapeutic antioxidant and beyond. The abstract describes Human participants. The abstract reports: Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice
This animal study examined Protective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. The abstract describes Mouse model. The abstract reports: And significant differences between the treatment group and the radiation-only groups were observed, showing that H could diminish the detriment induced by LDLTR and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer.
This uncontrolled human study examined Hydrogen therapy can be used to control tumor progression and alleviate the adverse events of medications in patients with advanced non-small cell lung cancer. The abstract describes Human participants; sample size 10; reported duration 5 months. The abstract reports: According to the results of tumor-gene mutations and drug-sensitivity tests, 10, 18, and 10 patients were enrolled into chemotherapy, targeted therapy, and immunotherapy groups…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial.
Consumption of hydrogen-rich water (HRW) has been shown to have anti-inflammatory and metabolic-modulatory benefits. A randomized, placebo-controlled trial was conducted to assess the potential blood uric acid-lowering effects of HRW consumption with different doses (low and high doses) and duration (4 and 8 weeks) in patients with hyperuricemia. The Placebo group consumed three bottles of ordinary drinking water (330 mL per bottle), the Low-HRW group consumed two bottles of HRW (330 mL per bottle, H ≥ 4.66 mg/L) and a bottle of ordinary water, and the High-HRW group consumed three bottles of HRW daily for…
Read MoreA basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level
This uncontrolled human study examined A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level. The abstract describes Human participants; sample size 10; reported duration 30 min. The abstract reports: H2 inhalation of at least 3% concentration for 30 min delivered enough HC, equivalent to the animal experiment levels, in the blood without compromising…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water.
This uncontrolled human study examined Dose-dependent inhibition of gastric injury by hydrogen in alkaline electrolyzed drinking water. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Hydrogen is effective in relieving the gastric injury induced by aspirin-HCl, and the inhibitory effect is dose-dependent. The reason behind this may be that…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSafety of intravenous administration of hydrogen-enriched fluid in patients with acute cerebral ischemia: initial clinical studies.
Most of the results regarding hydrogen (H2) therapy for acute cerebral ischemia are derived from in vitro studies and animal experiments, with only a few obtained from human trials with a limited number of subjects. Thus, there is a paucity of information regarding both the beneficial therapeutic effects as well as the side effects of H2 on acute cerebral ischemia in humans. We designed a pilot study to investigate single dose intravenous H2-administration in combination with edaravone, aiming to provide an initial estimate of the possible risks and benefits in…
Read MorePharmacokinetics of a single inhalation of hydrogen gas in pigs.
This animal study examined Pharmacokinetics of a single inhalation of hydrogen gas in pigs. The abstract describes Animal model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSafety of Prolonged Inhalation of Hydrogen Gas in Air in Healthy Adults.
This uncontrolled human study examined Safety of Prolonged Inhalation of Hydrogen Gas in Air in Healthy Adults. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of 2.4% hydrogen gas does not appear to cause clinically significant adverse effects in healthy adults. Although these data suggest that inhaled hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreFeasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study.
This uncontrolled human study examined Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome - First-in-Human Pilot Study. The abstract describes Human participants; sample size 107; hydrogen delivered as hydrogen inhalation. The abstract reports: HI in combination with TTM is a feasible therapy for patients with PCAS. (Circ J 2016; 80: 1870-1873). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
Molecular hydrogen (H) acts as a therapeutic antioxidant. Inhalation of H gas (1-4%) was effective for the improvement of cerebral infarction in multiple animal experiments. Thus, for actual applications, a randomized controlled clinical study is desired to evaluate the effects of inhalation of H gas.
Read MorePilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer Patients.
This observational study examined Pilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer Patients. The abstract describes Human participants; sample size 10; hydrogen delivered as hydrogen inhalation. The abstract reports: H gas inhalation combined with CCRT is feasible and safe for patients with LAHNC. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
This animal study examined Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These findings suggest that hydrogen-rich saline reduces airway inflammation and remodeling in OVA-exposed mice by inhibiting NF-κB. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China
This observational study examined Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 24 week. The abstract reports: The HI therapy is related to significant amelioration in BP levels with acceptable safety profile in Chinese hypertensive adults after 24 weeks of treatment,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs.
This animal study examined Pharmacokinetics of Hydrogen During Hydrogen-Saturated Saline Infusion in Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
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