Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.

This animal study examined Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species. The abstract describes Mouse model. The abstract reports: Recently, the production of mitochondrial reactive oxygen species (mtROS) in macrophages stimulated with LPS has been suggested to act as a trigger during the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fed mycotoxins contaminated diet.

This animal study examined Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fed mycotoxins contaminated diet. The abstract describes Porcine model; hydrogen delivered as hydrogen water. The abstract reports: It is well known that mycotoxins will lead a breakdown of the normally impeccable epithelial barrier, resulting in the development of a "leaky" gut. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats.

This uncontrolled human study examined Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Lack of dose responses of hydrogen and the presence of favorable effects with hydrogen water and intermittent hydrogen gas suggest that signal modulating activities…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydration bioanalyses of the effects of hydrogen-rich water (HRW).

This uncontrolled human study examined Hydration bioanalyses of the effects of hydrogen-rich water (HRW). The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Conclusions: These results suggest that measurable hydration effects in the human body may be achieved through regular intake of HEW. The findings of the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.

This animal study examined Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats. The abstract describes Rat model. The abstract reports: The data showed that the spatial recognition memory and fear memory of the rats treated with sevoflurane decreased compared with the control, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players.

This randomized controlled trial examined Hydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby players. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation; reported duration 3 weeks. The abstract reports: Two-way (supplementation and time) repeated-measures analyses of variance showed that NO, L-arginine, and tetrahydrobiopterin levels in the H inhalation group were significantly higher than…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.

This uncontrolled human study examined Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision. The abstract describes Human participants; reported duration 3 months. The abstract reports: Overall results demonstrated that an optimal oxidative balance can be restored and GERD symptoms can be reduced rapidly via the integration of ERW in…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.

This uncontrolled human study examined Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase. The abstract describes Human participants. The abstract reports: We found that hydrogen-rich medium could inhibit adhesion of monocytes to endothelial cells and decrease levels of adhesion molecules, whereas the levels of transepithelial/endothelial…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways.

This animal study examined Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways. The abstract describes Animal model; hydrogen delivered as injected or infused hydrogen; reported duration 6 weeks. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Protective effects of hydrogen-rich medium on lipopolysaccharide-induced monocytic adhesion and vascular endothelial permeability through regulation of vascular endothelial cadherin.

This in vitro or cellular study examined Protective effects of hydrogen-rich medium on lipopolysaccharide-induced monocytic adhesion and vascular endothelial permeability through regulation of vascular endothelial cadherin. The abstract describes HUVEC model. The abstract reports: Fluorescence results showed that, compared with control cells, the VE-cadherin in LPS cells was in-complete at the cell joints. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Early Aerobic Exercise Combined with Hydrogen-Rich Saline as Preconditioning Protects Myocardial Injury Induced by Acute Myocardial Infarction in Rats.

This animal study examined Early Aerobic Exercise Combined with Hydrogen-Rich Saline as Preconditioning Protects Myocardial Injury Induced by Acute Myocardial Infarction in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Neutral pH hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with intracellular oxidant repression.

This in vitro or cellular study examined Neutral pH hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with intracellular oxidant repression. The abstract describes Cell culture / in vitro model. The abstract reports: NHE water diminished hydroxyl radicals as demonstrated by ESR in a cell-free system. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation].

This animal study examined [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Delayed resuscitation for scalded rats with hydrogen-rich saline is helpful in the recovery of systolic pressure, and it can ameliorate lung tissue injury caused…. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

In vivo quantification of hydrogen gas concentration in bone marrow surrounding magnesium fracture fixation hardware using an electrochemical hydrogen gas sensor.

This animal study examined In vivo quantification of hydrogen gas concentration in bone marrow surrounding magnesium fracture fixation hardware using an electrochemical hydrogen gas sensor. The abstract describes Rabbit model. The abstract reports: Here, the in vivo measurement of H surrounding fracture fixation devices implanted in vivo is demonstrated. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More

Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.

This animal study examined Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition. The abstract describes Mouse model. The abstract reports: 2% H can protect against TBI-induced lung injury by inhibiting NLRP3 inflammasome activation, thereby alleviating inflammation and inhibiting apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

Read More