Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, hRS decreased P-selectin expression, release of thromboxane B2, ROS, and fibrinogen binding, but enhanced NO levels in H₂O₂-exposed platelets. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn For human ex vivo studies, the researchers collected blood samples from six healthy humans and added normal saline or hydrogen-rich saline to blood and platelet-rich plasma, collagen-induced…
Read ArticleIn rats, however, the reduction of the expression of 8-OHdG, the decrease in the neuronal injury in the hippocampal CA1 sector, and the attenuation in brain water content…
Read ArticleIn a laboratory model, molecular hydrogen inhalations in both regimens caused a decrease in the number of circulating endothelial cells; the most pronounced effect was observed after repeated…
Read ArticleIn male Wistar rats, during mild SI, H₂ reduced plasma surges of proinflammatory cytokines (TNF-α and IL-6) while caused an increase in plasma IL-10 (anti-inflammatory cytokine) and prevented…
Read ArticleThis preclinical study evaluated molecular hydrogen in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to…
Read ArticleHydrogen improved microvascular endothelial-cell viability partly through PI3K/Akt/GSK3β activation and inhibition of autophagy in a traumatic-brain-injury model. These findings come from a laboratory model and suggest molecular hydrogen's…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Hydrogen (H₂) is colorless, odorless, and the lightest of gas molecules. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn vitro, LPS treatment increased the expression levels of STIM1 and Orai1 in PMVECs, while H₂ reversed these changes. The authors concluded that the present study suggested that…
Read ArticleIn a laboratory model, thus, 3%-hydrogen gas inhalation is suggested to potentially improve both the erythrocyte rheological/morphologic behaviors and the leucocyte phagocytosis-associated activity, concurrently with the enhanced antioxidant…
Read ArticleIn Wistar rats, serum levels of endotoxin, syndecan-1, malondialdehyde, and tumor necrosis factor-α decreased, whereas superoxide dismutase levels increased, indicating that inhalation of 2% hydrogen attenuated the damage…
Read ArticleIn 14 healthy participants with crossover design, ln SDNN was significantly increased after HRW administration when compared to placebo in 45 min (HRW: 4.41 ± 0.42 ms, placebo:…
Read ArticleIn rats, H₂ and XOR-I both suppressed MAP reduction and improved survival rates. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further…
Read ArticleThese preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen inhalation blood pressure…
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