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Latest Molecular Hydrogen Articles

130 Articles

Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.

By H2HUBB Jul 22, 2026 0 Comments

Hydrogen improved microvascular endothelial-cell viability partly through PI3K/Akt/GSK3β activation and inhibition of autophagy in a traumatic-brain-injury model. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.

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Hydrogen-Rich Medium Attenuated Lipopolysaccharide-Induced Monocyte-Endothelial Cell Adhesion and Vascular Endothelial Permeability via Rho-Associated Coiled-Coil Protein Kinase.

By H2HUBB Jul 22, 2026 0 Comments

The researchers found that hydrogen-rich medium could inhibit adhesion of monocytes to endothelial cells and decrease levels of adhesion molecules, whereas the levels of transepithelial/endothelial electrical resistance values…

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Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, treatment with hydrogen reduced Ang II- or AAC-induced oxidative stress, which was reflected by diminishing the induction of reactive oxygen species (ROS) in Ang…

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Protective effects of hydrogen-rich medium on lipopolysaccharide-induced monocytic adhesion and vascular endothelial permeability through regulation of vascular endothelial cadherin.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, compared with LPS, there was an obvious reduction in the conglutination of LPS+H₂ cells, a reduction in VCAM-1, ICAM-1, and E-selectin levels, and a…

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[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation].

By H2HUBB Jul 22, 2026 0 Comments

In rats, delayed resuscitation for scalded rats with hydrogen-rich saline is helpful in the recovery of systolic pressure, and it can ameliorate lung tissue injury caused by reperfusion…

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Inhalation of 2% Hydrogen Improves Survival Rate and Attenuates Shedding of Vascular Endothelial Glycocalyx in Rats with Heat Stroke.

By H2HUBB Jul 22, 2026 0 Comments

In Wistar rats, serum levels of endotoxin, syndecan-1, malondialdehyde, and tumor necrosis factor-α decreased, whereas superoxide dismutase levels increased, indicating that inhalation of 2% hydrogen attenuated the damage…

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Hydrogen improves cell viability partly through inhibition of autophagy and activation of PI3K/Akt/GSK3β signal pathway in a microvascular endothelial cell model of traumatic brain injury.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, more importantly, inhibition of PI3 K/Akt/GSK3β signal pathway or activation of autophagy reduced the protective effect of hydrogen on cell viability, indicating that such…

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Hydrogen‑rich saline promotes neuronal recovery in mice with cerebral ischemia through the AMPK/mTOR signal‑mediated autophagy pathway.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, the infarct volume of mice in the HRS‐H group decreased significantly compared to that of the distal middle cerebral artery occlusion (dMCAO) group. These…

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Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, hydrogen up-regulated H2S levels via promoting the expression of CBS in the hippocampus, and its treatment alleviated oxidative stress via activating the expression of Nrf2 and…

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Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, HRW treatment improved neurological function and tended to improve overall survival but without significant difference. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within…

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Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.

By H2HUBB Jul 22, 2026 0 Comments

CV showed no significant improvement between the control and H₂ groups. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research…

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Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats.

By H2HUBB Jul 22, 2026 0 Comments

In rats, the Kaplan-Meier analysis showed that H₂ significantly improved the 4 h-survival endpoint (log-rank P = 0.025 vs. placebo). These preclinical findings add evidence supporting molecular hydrogen's…

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Protection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest.

By H2HUBB Jul 22, 2026 0 Comments

In an animal model, after the CPR, blood pH, base excess, and lactate showed significantly smaller deterioration in the hydrogen group than in the control group. These preclinical…

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Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.

By H2HUBB Jul 22, 2026 0 Comments

In a laboratory model, hydrogen inhalation reduced the expression of these inflammatory and apoptotic makers in the vessels, brain edema, microthrombi formation, and vasospasm in rats with SAH…

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Rhupus Syndrome With Multiple Drug Intolerances Managed by Reduced-dose Rituximab and Adjunctive Molecular Hydrogen Therapy: A Case Report.

By H2HUBB Jul 22, 2026 0 Comments

/AIM: Rhupus syndrome, an overlap of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), is a rare condition characterized by heterogeneous clinical manifestations and difficul, this case suggests…

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