Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, the 7-day survival rate of severe sepsis mice was 0; the 7-day survival rate was increased to 60% in hydrogen treatment group, with statistical significance in variables compared with model group (P<0.05). These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn male Sprague-Dawley rats,, the researchers found that Pec or HAS, which enhance H₂ generation in the large intestine, alleviated hepatic IR injury. These preclinical findings add evidence…
Read ArticleIn isolated guinea pig ileum segments in a peristaltic tissue bath, hydrogen shortened colonic transit time by 47% in the proximal colon, and by 10% in the distal…
Read ArticleIn Sprague-Dawley rats, intragastric administration of lactulose substantially increased breath hydrogen concentration. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleThis narrative review examined the types of H₂ donors and their pharmacokinetics in vivo. There are various methods of administration of H₂, mainly including inhaling hydrogen gas, drinking…
Read ArticleThese findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
Read ArticleIn 0 patients with progressive muscular dystrophy (PMD), less prominent effects with the double-blind trial compared to the open-label trial were likely due to a lower amount of…
Read ArticleIn an animal model, either HRW or LAC treatments were also revealed to prevent abnormal intestinal morphological changes, disintegrate tight junctions, and restore the expression and distribution of…
Read ArticleIn rats, the Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. These preclinical findings add…
Read ArticleIn an animal model, the incidence of bacterial translocation at 24 h after CLP as assessed by cultivation of mesenteric lymph nodes and blood was significantly decreased in…
Read ArticleIn mice, therapy with 2% H₂ increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels but increased HO-1 levels in WT…
Read ArticleIn mice, the load of blood and peritoneal lavage bacteria was increased, and H₂ treatment can significantly reduce it. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleUnder pH 8.5, 0.07, 0.22 and 0.84 ppm hydrogen exhibited a high correlation with inhibitory effects showed by erosion area, MPO activity and MDA content in the stomach.…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline treatment decreased the neutrophil infiltration, the lipid membrane peroxidation, NF-kappaB activation and the pro-inflammatory cytokine interleukin IL-1beta and TNF-alpha in the lung…
Read ArticleIn rats, combined early fluid resuscitation and hydrogen inhalation may protect the lung and intestine of the septic shock rats from the damage induced by oxidative stress and…
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