Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. Molecular hydrogen (H₂) and formate (HCOO-) are metabolic end products of many primary fermenters in the mammalian gut. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes…
Read ArticleIn this animal study, the authors report that HRW treatment significantly attenuated disease severity by reducing disease activity index, preserving colon length, decreasing pro-inflammatory cytokines, and partially restoring…
Read ArticleIn rats, pEG led to a significant increase in exhaled H₂ (35 ppm [10-73] compared with control 7 ppm [2-15]; p = 0.001). These preclinical findings add evidence…
Read ArticleIn mice, taking together, these results suggested that besides a high dose of H₂ towards IR-sited tissues for inflammation scavenging and anti-IR, oral administration of Zn-Fe can also…
Read ArticleIn mice, hydrogen gas concentrations in maternal livers and whole fetuses in EFA-FOS were significantly higher than those in CONT and EFA, respectively (P <.05). These preclinical findings…
Read ArticlePropose that the cardiovascular benefits of alpha-glucosidase inhibitors are partly attributable to their ability to neutralise oxidative stress via increased production of H(2) in the gastrointestinal tract. This…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. discuss the therapeutic role of alkaline-reduced water (ARW) on GI diseases and existing studies on ARW related to GI diseases.…
Read ArticleIn an animal model, however, since hydrogen is a substance with no side effects, it can be inhaled for a long period of time, and the intestinal microflora…
Read ArticleH2HUBB PLAIN-LANGUAGE TAKEAWAY The study adds to the molecular-hydrogen evidence base, but the available record does not support a firm conclusion about therapeutic benefit. Hydrogen gastrointestinal study 1969:…
Read ArticleIn 118 participants, a significant decline in fTBUT was observed in the placebo group (p = 0.04), but not the H₂-producing group (p = 0.26). These findings add…
Read ArticleIn a laboratory model, hydrogen-rich medium can effectively attenuate LPS-induced dysfunction of intestinal epithelial barrier in human Caco2 cells by ameliorating cell viability as well as regulating claudin-1…
Read ArticleIn mice, exogenous H₂ reprograms colonocyte metabolism by regulating the H₂-gut microbiota-SCFAs axis and strengthens the intestinal barrier by modulating specific mucosa-associated mucolytic bacteria, wherein improved microbial hydrogen…
Read ArticleIn 27 patients with diarrhea-predominant IBS, the IBS quality-of-life score significantly improved from 57.2 to 30.8 in the ARW group; this improvement was significantly greater than the slight…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Increasing evidence suggests that hydrogen, as an inert gas, is crucial for immunity, inflammation, and oxidative stress and plays a…
Read ArticleIn Following reperfusion, segments of terminal jejunum were rapidly taken and transferred into isolated organ bath and responses to KCl were recorded, hydrogen-rich saline treatment significantly attenuated the…
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