Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn a laboratory model, molecular hydrogen treatment promoted PKM2 lactylation without affecting total PKM2 expression. The authors concluded that molecular hydrogen can promote PKM2 lactylation to restrain NLRP3…
Read ArticleIn mice, the pivotal proteins involved in endoplasmic reticulum (ER) stress, including p-eIF2α, ATF4, XBP1s and CHOP, were dramatically reduced after HRW treatment in contrast to the control…
Read ArticleIn rats, the oxidative stress levels of MDA and MPO in the gastric tissues increased significantly in the aspirin-treated group compared with the HRW group (2.43 ± 0.145…
Read ArticleIn vitro analysis of cytokine levels after LPS treatment of cultured macrophages showed an increase of interleukin-10 by hydrogen regardless of the presence of nitric oxide. The authors…
Read ArticleIn an animal model, control (n = 4) and hydrogen (n = 4) groups with similar baseline characteristics were included. These preclinical findings add evidence about the molecular-hydrogen…
Read ArticleThe findings suggest that treatment with molecular hydrogen may affect microbiota profiling and suppress intestinal injury in HFD-loaded SAMP8. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThese findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
Read ArticleIn rats, the obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the expression of…
Read ArticleIn mice, HRW and sulfasalazine significantly improved bodyweight, DAI, mucosal damage, crypt loss, and spleen weight compared to control. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn In this double-blind, randomized, crossover study, participants ingested H₂-producing milk that induced intestinal bacterial H₂ production or a placebo on the trial day, 4 h before performing…
Read ArticleIn mice, H₂ treatment attenuated serum interleukin-6 and tumor necrosis factor-α levels at 24 h after CLP, and blood glucose levels were maintained in the H₂-treated group. These…
Read ArticleIn participants with IFG were enrolled in a randomized, H₂ slightly improved metabolic abnormalities and gut microbiota dysbiosis, providing a novel target and theoretical basis for the prevention…
Read ArticleThis narrative review examined the basic research and clinical applications of HRW consumption to support its use for daily health and clinical treatment. Clinically, HRW has been used…
Read ArticleIn An in vitro model of oral administration showed that pretreatment in artificial gastric juice did not affect hydrogen generation, the addition of egg white reduced hydrogen generation…
Read Article