Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In mice, despite the speculation, the effect of H₂ water was still observed in ghrelin-KO PD model mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read Articlein vitro production of both TNF-alpha and IFN-gamma by ConA-stimulated spleen lymphocytes was significantly inhibited by the introduction of H(2), systemic antibiotics significantly decreased the level of H(2)…
Read ArticleIn mice, H₂ inhalation improved gut microbiota, including increasing the abundance of Lachnospiraceae and Clostridia, and decreasing the abundance of Prevotellaceae and Muribaculaceae, and also improved intestinal barrier…
Read ArticleIn mice, at day-7, DSS-induced pathogenic outcomes including, loss of body weight, increase of colitis score, pathogenic shortening of colon length, elevated level of IL-12, TNF-alpha and IL-1beta…
Read ArticleThe researchers found hydrogen-rich solutions treatment groups showed the decreased MDA, MPO, IL-6 and TNF-α levels, and increased SOD, IL-10 comparing with those of non-hydrogen solutions administration groups.…
Read ArticleIn rats, iR-induced upregulation of proinflammatory cytokine mRNAs such as IL-6 was mitigated by hydrogen treatment. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the…
Read ArticleIn rats, increased expression of TJ proteins occludin and ZO-1 by reducing various parameters of ERS and ERS-induced apoptosis evidenced by down-regulation of the protein levels of GRP78,…
Read ArticleIn an animal model, HRW treatment increased the hydrogen levels of the stomach and duodenum. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes…
Read ArticleIn rats, hRSS is effective in reducing the intestinal damage caused by an IRI: HRSS has the potential to reduce the detrimental effects of intestinal anastomosis performed after…
Read ArticleIn rats, however, hydrogen-rich saline treatment significantly increased the 24-h survival of rats to 53.33% (8 of 15 rats) in the HRS1 group and 86.67% (13 of 15…
Read ArticleIn Tissue oxidative stress was analyzed with immunostaining for 8-hydroxy-2'-deoxyguanosine (8-OHdG), hydrogen mitigated such apoptosis at the crypt base, and the LGR5 expression of the tissues was higher…
Read ArticleIn This study utilized next-generation sequencing (NGS) to assess mRNA and miRNA expression in EHW-treated Caco-2 cells, eHW treatment significantly decreased the levels of miR-429 and miR-200c-3p and…
Read ArticleIn rats, this study provides biochemical and histomorphological evidence that HRSS prevents intestinal damage in I/R injury caused by volvulus. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn male C57BL/6 mice, HRW treatment partially ameliorated colitis symptoms, improved histopathological changes, significantly increased glutathione (GSH) concentration and decreased TNF-α level. These preclinical findings add evidence supporting…
Read ArticleIn rats, meanwhile, the increased MPO level in the EHW-administered group significantly reduced 2 ( p = 0.0011) and 4 ( p = 0.0009) days post TNBS treatment…
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