Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. Gas therapies, including inhaled nitric oxide (NO), molecular hydrogen (H₂), xenon (Xe), and argon (Ar), have emerged as promising neuroprotective agents. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions,…
Read ArticleIn mice, hydrogen gas suppressed the increase in eye-scratching behavior. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in…
Read ArticleIn bone marrow, the reduction in CD11b+Ly-6G+ neutrophils observed in AAD mice was significantly attenuated by H₂ inhalation. In the aortic wall, H₂ reduced MMP-9 and CXCL1 expression,…
Read ArticleIn rats, hydrogen improved PaO(2)/FIO(2) and PVO(2)/FIO(2) from the arterial and pulmonary venous blood in recipients and decreased the lung injury score in grafts from brain-dead donors. These…
Read ArticleIn the present study, the researchers found that inhalation of H₂ (2%) or hyperoxia (98%) alone improved the 14-day survival rate of septic mice with moderate cecal ligation…
Read ArticleIn rats, the intracellular surfactant pool, tissue adenosine triphosphate (ATP) levels and heat shock protein 70 (HSP70) expression increased in the hydrogen-treated grafts. These preclinical findings add evidence…
Read ArticleIn Peripheral blood mononuclear cells were isolated using Ficoll solution and labeled with fluorescent antibodies (BD Biosciences, San Jose, CA, USA), after 2 weeks of hydrogen inhalation, statistically…
Read ArticleIn 70 patients with percentages in parentheses, only 28.6% (2/7) participants had improved CT L/S in the placebo group after the trial, while 75% (6/8) participants in hydrogen/oxygen…
Read ArticleIn 100 patients with brain glioma, similarly, S100β, NSE, GFAP, and MDA levels were found to be lower in the hydrogen group (0.41±0.09 μg/L, 8.24±1.64 ng/mL, 0.71±0.23 pg/mL,…
Read ArticleThe results suggest activation of Nrf2/Keap1 pathway as well as increased SOD1 protein expression in the group treated with H₂. These preclinical findings add evidence supporting molecular hydrogen's…
Read ArticleIn rats, compared with controls, the H₂ and Mg groups had significantly reduced total depolarization and hypoperfusion times. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential…
Read ArticleIn mice, these levels decreased following the treatment with 2% H₂ inhalation. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways…
Read ArticleThis systematic review examined hydrogen (H₂ ) therapy demonstrates selective antioxidant and anti-inflammatory properties with potential therapeutic value for multiple forms of hearing loss, though consolidated evidence is…
Read ArticleMore and more studies suggest that radical oxygen species (ROS) play an important role in the development of diabetic erectile dysfunction (ED) and antioxidants can markedly decrease the…
Read ArticleIn an animal model, abstract 11983: Delayed Inhalation of Hydrogen Mitigates Neurological Dysfunction in a Porcine Model of Cardiac Arrest and Cardiopulmonary Resuscitation In the present study, the…
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