Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In 64 patients with COVID-19, the present findings showed that hydrogen/oxygen inhalation shortened the virus shedding duration, decreased the inflammatory factor levels, as well as resolved the pulmonary lesions compared to oxygen inhalation alone, thereby reducing the occurrence of severe cases in…
Read ArticleIn this rat model cardiac arrest and CPR, gender did not affect resuscitation but associated with neurological outcome. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes,…
Read ArticleIn 87 patients with early-stage ILD, a significant decrease in CPI and improvement in DLCO-sb were observed in the hydrogen group compared with those in the control group.…
Read ArticleIn rats, the hydrogen concentration in the heart, liver, and spleen showed an increasing trend over time, and all exhibited a significant increase in hydrogen concentration at 5…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. However, limitations include hydrogen termination upon material depletion and reduced bioavailability at targeted lesions. The reviewed evidence adds support for…
Read ArticleIn mice, the excellent small-sized therapeutic nanoparticles the researchers designed and synthesised can easily cross the blood-brain barrier to the site of inflammation in the brain and achieve…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Direct delivery of hydrogen gas and HRW to the respiratory and digestive systems can enhance the bioavailability of H₂ at…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Many clinical trials are constrained by small sample sizes and limited patient diversity, with aged and female patients frequently under-represented,…
Read ArticleIn mice, si-based agents are effective against allergic bronchial asthma and may serve as superior materials for hydrogen therapy. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the therapeutic potential of H₂ in preventing and treating sensorineural hearing loss and aims to inform future research directions. After 4 weeks of H₂…
Read ArticleThe researchers observed significant dilatation and higher Z scores in the left coronary artery (LCA) in D21 and D28 in mice after LCWE treatment compared to the control…
Read ArticleIn mice, hydrogen inhalation attenuated the immune response; decreased the levels of IL-4, IL-5 and IL-13; and further increased the mRNA expression levels of Treg-associated cytokines, namely, IL-10…
Read ArticleIn an animal model, although lung neutrophil counts were significantly higher in the HI-H₂ group, pulmonary gas exchange remained preserved, with no significant differences in arterial blood gases,…
Read ArticleIn rats, hydrogen-rich saline reversed these changes and relieved morphological renal injury and I/R-induced apoptosis, while no significant changes were observed in the nitrogen-rich saline-treated group compared with…
Read ArticleIn Sprague-Dawley rats, the antibiotics suppressed the regeneration-promoting effect of lactulose by reducing hydrogen production, whereas supplementing hydrogen by hydrogen-rich saline would get a similar regeneration-promoting effect as…
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