H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.

This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.

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In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation.

This animal study examined In Situ Nanoreactor for Photosynthesizing H Gas To Mitigate Oxidative Stress in Tissue Inflammation. The abstract describes Mouse model. The abstract reports: Experimental results indicate that the Lip NR system that can photosynthesize H gas has great potential for mitigating oxidative stress in tissue inflammation. This is an automated editorial draft based on the abstract and requires source review before publication.

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The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.

This animal study examined The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice. The abstract describes Mouse model. The abstract reports: In the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema.

This in vitro or cellular study examined Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: As a more convenient way than inhaling H2, hydrogen saline exhibits a protective effect against inflammation and it might provide a novel therapeutic approach…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model

This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila.

This animal study examined Impact of molecular hydrogen treatments on the innate immune activity and survival of zebrafish (Danio rerio) challenged with Aeromonas hydrophila. The abstract describes Zebrafish model; hydrogen delivered as hydrogen water. The abstract reports: We have found an increased survival rate of bacteria-challenged zebrafish subjected to the HRW immersion treatment. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.

This animal study examined Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.

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Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages.

This in vitro or cellular study examined Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages. The abstract describes Cell culture / in vitro model. The abstract reports: Molecular hydrogen exerts a regulating role in the release of pro- and anti-inflammatory cytokines in LPS-stimulated macrophages, and this effect is at least partly…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation.

This animal study examined Hydrogen-rich saline resuscitation alleviates inflammation induced by severe burn with delayed resuscitation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: We found that resuscitation by hydrogen-rich saline alleviated inflammation significantly. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Ameliorates Allergic Rhinitis by Reversing the Imbalance of Th1/Th2 and Up-Regulation of CD4+CD25+Foxp3+Regulatory T Cells, Interleukin-10, and Membrane-Bound Transforming Growth Factor-β in Guinea Pigs

This animal study examined Hydrogen-Rich Saline Ameliorates Allergic Rhinitis by Reversing the Imbalance of Th1/Th2 and Up-Regulation of CD4+CD25+Foxp3+Regulatory T Cells, Interleukin-10, and Membrane-Bound Transforming Growth Factor-β in Guinea Pigs. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells.

This animal study examined Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that oral intake of hydrogen-rich water abolishes an immediate-type allergic reaction in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.

This uncontrolled human study examined Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses.

This animal study examined Hydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responses. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Mice that consumed HRW for ≥P4 weeks ran significantly longer distances, showed less muscle fatigue, and had lower levels of markers of oxidative stress,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.

This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular Hydrogen Therapy for SLE-PAH: Case Report on Immune Marker Modulation

This case report or case series examined Molecular Hydrogen Therapy for SLE-PAH: Case Report on Immune Marker Modulation. The abstract describes Human participants. The abstract reports: This case study highlights the potential efficacy of molecular hydrogen therapy in a patient with SLE-PAD and decompensated right-sided heart failure precipitated by sepsis.…. This is an automated editorial draft based on the abstract and requires source review before publication.

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