The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
This in vitro or cellular study examined The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide-triggered NLRP3 inflammasome activation in macrophages by targeting the mitochondrial reactive oxygen species. The abstract describes Mouse model. The abstract reports: Recently, the production of mitochondrial reactive oxygen species (mtROS) in macrophages stimulated with LPS has been suggested to act as a trigger during the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOpen-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies.
This randomized controlled trial examined Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies. The abstract describes Human participants; sample size 10; reported duration 12 weeks. The abstract reports: Hydrogen-enriched water improves mitochondrial dysfunction in MM and inflammatory processes in PM/DM. Less prominent effects with the double-blind trial compared to the open-label trial…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats.
This animal study examined Hydrogen gas attenuates sevoflurane neurotoxicity through inhibiting nuclear factor κ-light-chain-enhancer of activated B cells signaling and proinflammatory cytokine release in neonatal rats. The abstract describes Rat model. The abstract reports: The data showed that the spatial recognition memory and fear memory of the rats treated with sevoflurane decreased compared with the control, and the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMagnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
This animal study examined Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: RESULTS: MGNs exhibited a two-dimensional structure and enabled sustained hydrogen release, particularly under acidic conditions. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury
This animal study examined Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent studies have demonstrated the potential neuroprotective effects of molecular hydrogen on TBI. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
This animal study examined Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. The abstract describes Mouse model; sample size 1; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Activation of mast cells following intracerebral hemorrhage contributed to increase of blood-brain barrier permeability and brain edema. Hydrogen inhalation preserved blood-brain barrier disruption by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
This uncontrolled human study examined Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Our results demonstrated that TBI-challenged rats exhibited significant brain injuries that were characterized by decreased survival rate and increased BBB permeability, brain edema, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury.
This animal study examined Hydrogen-rich saline alleviates early brain injury through inhibition of necroptosis and neuroinflammation via the ROS/HO-1 signaling pathway after traumatic brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen, which is a slight and specific cytotoxic oxygen radical scavenger, has been demonstrated to ameliorate early brain injury (EBI) through reactive oxygen species…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBeneficial effects of hydrogen-rich saline on early burn-wound progression in rats.
This animal study examined Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen can attenuate early wound progression following deep burn injury. The beneficial effect of hydrogen was mediated by attenuating oxidative stress, which inhibited apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition.
This in vitro or cellular study examined Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition. The abstract describes Epithelial cell model. The abstract reports: We have discovered a novel pattern of wound healing induced by molecular hydrogen treatment. This is the first time to reveal the direct link between…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells.
This in vitro or cellular study examined Hydrogen ameliorates oxidative stress via PI3K-Akt signaling pathway in UVB-induced HaCaT cells. The abstract describes HaCaT keratinocyte model. The abstract reports: All of the results indicated that hydrogen decreased the levels of reactive oxygen species, 8‑iso‑prostaglandin F2α and malondialdehyde, and promoted the UVB exposure‑induced expression…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap.
This animal study examined Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our findings suggest that HRS mitigates I/R injury by decreasing inflammation and, therefore, has the potential for application as a therapy for improving skin…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePositive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.
This animal study examined Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we investigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that…. This is an automated editorial draft based on the abstract and requires source review before publication.
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