Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.
This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic
This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice.
This animal study examined Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: The results revealed that HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents
This in vitro or cellular study examined Combined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents. The abstract describes Keratinocyte model; hydrogen delivered as hydrogen water. The abstract reports: Remarkably, the combined use of HW and EBND exhibited particularly robust results. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLocal Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.
This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
This animal study examined Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: The Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProphylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.
This animal study examined Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 5 min. The abstract reports: Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status.
This uncontrolled human study examined The protective effects of molecular hydrogen in sepsis-associated encephalopathy: current status. The abstract describes Human participants. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy
This animal study examined Molecular hydrogen-mediated SIRT1 activation alleviates sepsis-associated encephalopathy by promoting mitophagy. The abstract describes Mouse model. The abstract reports: This study demonstrates that inhalation of 2% H2 exerts significant protective effects against SAE, in which SIRT1 plays a pivotal role by modulating PINK1-dependent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway.
This in vitro or cellular study examined Molecular hydrogen attenuates sepsis-induced neuroinflammation through regulation of microglia polarization through an mTOR-autophagy-dependent pathway. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: Sepsis-associated encephalopathy (SAE) is the cognitive impairment resulting from sepsis and is associated with increased morbidity and mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreChronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis.
This uncontrolled human study examined Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: Our results indicate that (1) chronic exposure of hydrogen gas is a simple, safe and promising therapeutic strategy to prevent memory loss in patients…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAug 2019(mitochondrial dysfunction ,sepsis, autophagy)Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis
This animal study examined Aug 2019(mitochondrial dysfunction ,sepsis, autophagy)Hydrogen alleviates mitochondrial dysfunction and organ damage via autophagy-mediated NLRP3 inflammasome inactivation in sepsis. The abstract describes Mouse model. The abstract reports: The results demonstrated that LPS and ATP led to NLRP3 inflammasome pathway activation, excessive cytokine release, mitochondrial dysfunction and the activation of autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas presents a promising therapeutic strategy for sepsis.
This uncontrolled human study examined Hydrogen gas presents a promising therapeutic strategy for sepsis. The abstract describes Human participants. The abstract reports: Recently, some studies have found that molecular hydrogen is a new therapeutic gas. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis.
This animal study examined Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline; reported duration 7 days. The abstract reports: In the results, the 7-day survival rate was significantly improved in the H2 group versus the control group (69% vs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.
This animal study examined Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release. The abstract describes Mouse model. The abstract reports: The results showed that therapy with 2% H2 increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels…. This is an automated editorial draft based on the abstract and requires source review before publication.
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