Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, no significant differences in dissolved H₂ or ORP values were observed in the HRW samples either at 4 °C or at 25 °C within 24 h. These preclinical findings add evidence about the molecular-hydrogen effects, outcomes, and biological pathways measured…
Read ArticleIn rats, the mechanism of this phenomenon suggests that H₂ may have effectively attenuated AOC‑induced inflammatory and oxidative damage, and decreased matrix metalloproteinase activity. These preclinical findings add…
Read ArticleIn rats, the hydrogen-rich UW solution group also showed less oxidative damage and hepatocyte apoptosis than the control group, and the expression of proinflammatory cytokines tended to be…
Read ArticleIn mice, the HW group showed a smaller decrease in hepatic cholesterol; however, stronger antioxidative effects in serum and lower peroxisome proliferator-activated receptor-α expression in the liver were…
Read ArticleIn an animal model, liver samples in the group with inhaled hydrogen showed a statistically significant reduction in histological changes compared to the control group. These preclinical findings…
Read ArticleThis publication examined molecular hydrogen using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read ArticleIn mice, HRW attenuated malondialdehyde level, restored glutathione depletion and increased superoxide dismutase, glutathione peroxidase and catalase activities in the liver. These preclinical findings add evidence supporting molecular…
Read ArticleIn Sprague-Dawley rats, long-term HRW consumption significantly reduced LPS-induced inflammatory cell infiltration in liver tissue, suppressed the abnormal elevation of pro-inflammatory factors, and maintained relatively stable expression levels…
Read ArticleIn mice, among these, Acaca, Fasn, and CD36 were decreased ( Figures 2G-I ), while Mttp and Apob were increased by high dose H₂ therapy ( Figures 2N,O…
Read ArticleIn the present study, the researchers found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated hepatic inflammatory factor…
Read ArticleIn mice, H₂ inhalation improved gut microbiota, including increasing the abundance of Lachnospiraceae and Clostridia, and decreasing the abundance of Prevotellaceae and Muribaculaceae, and also improved intestinal barrier…
Read ArticleIn mice, intraperitoneal injection of H₂ improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing serum ALT and AST levels, hepatic…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn mice, the study verified a catalytic strategy of combining PdH nanoparticles and hydrogen inhalation, which exhibited enhanced anti-inflammatory effect for CLD treatment. These preclinical findings add evidence…
Read ArticleIn 30 participants with NAFLD, HRW was well-tolerated, with no significant changes in liver enzymes and a trend of improved lipid profile and reduced lactate dehydrogenase levels. These…
Read Article