Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. The delivery of molecular hydrogen (H₂) is increasingly recognized for its potential in precision immunomodulation, primarily through multiple pathways such as antioxidant action, modulation of inflammatory factors, and inhibition of apoptosis. To address limitations…
Read ArticleIn contrast, bile production and lactate dehydrogenase leakage therein were both significantly improved in HyFACS-HA and -PV + HA (P < 0.01), representing the superiority of the arterial…
Read ArticleIn 30 patients with NAFLD and 15 healthy volunteers were included in this clinical trial, after 8 weeks of adjuvant therapy with HRW, the concentration of CoQ10 in…
Read ArticleIn Sprague-Dawley rats, H₂ improved the hepatic histological changes and glucose tolerance, decreased the liver function parameters of plasma alanine aminotransferase and aspartate aminotransferase, and relieved liver inflammation.…
Read ArticleIn mice, H₂ treatment reduced serum TC levels in the Alcohol+H₂ group when compared with those in Alcohol group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleIn rats, the data indicate that 1-month treatment of N-acetylcysteine or hydrogen-rich saline significantly ameliorated systemic and splanchnic hyperdynamic circulation, corrected hepatic endothelial dysfunction, and decreased intrahepatic resistance…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Further, the article reveals ex vivo hydrogen application in liver protection. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn an animal model, white blood cells in the HRS-10 group were reduced compared with the IRI group (P < 0.01). These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, inhalation of hydrogen gas at 2% concentration for 1 h significantly reduced the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, the expression of cytokines,…
Read ArticleIn rats, compared to lactated Ringer's solution, hydrogen-rich solution, or hyperoxygenated solution groups, serum AST and alanine aminotransferase levels and IL-6, tumor necrosis factor-α, and malondialdehyde expression in…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. These preclinical…
Read ArticleIn rats, 10 ml/kg hydrogen-enriched saline treatment significantly reduced ALT to 284.1 ± 34.0 IU/l after 2 hours of reperfusion ( p < 0.05). In contrast, histological evidence…
Read ArticleIn C57BL/6 mice, hCH significantly improved liver function, reduced serum inflammatory cytokines, and inhibited hepatocyte apoptosis, and also induced the PI3K-Akt pathway activation. These preclinical findings add evidence…
Read ArticleIn rats, hydrogen gas reduced hepatic reperfusion injury after prolonged cold preservation via the maintenance of portal flow, by protecting mitochondrial function during the early phase of reperfusion,…
Read ArticleThe researchers found that saturated hydrogen saline treatment efficiently decreased the activation of ERK and JNK, while promoting the activation of p38 (P<0.05 compared with LPS), suggesting the…
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