Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
This animal study examined Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways. The abstract describes Rat model. The abstract reports: Rats exposed 2 h daily to H either by drinking HRW (H dissolved in HO) or by breathing 4% H gas showed reduced lipogenesis and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBiological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial.
This randomized controlled trial examined Biological Effects of Hydrogen Water on Subjects with NAFLD: A Randomized, Placebo-Controlled Trial. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water. The abstract reports: The favorable trends in this study in conjunction with previous animal and clinical findings suggest that HRW may serve as an important adjuvant therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling.
This in vitro or cellular study examined Hydrogen-rich water protects against liver injury in nonalcoholic steatohepatitis through HO-1 enhancement via IL-10 and Sirt 1 signaling. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl4-Induced Chronic Liver Injury in Rats
This animal study examined A Preliminary Study on the Effect of Hydrogen Gas on Alleviating Early CCl4-Induced Chronic Liver Injury in Rats. The abstract describes Rat model; sample size 32. The abstract reports: We found that CCl can induce significant steatosis in hepatocytes. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats.
This animal study examined Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice.
This in vitro or cellular study examined Molecular hydrogen improves obesity and diabetes by inducing hepatic FGF21 and stimulating energy metabolism in db/db mice. The abstract describes Fibroblast model. The abstract reports: To examine how drinking H(2)-water improves obesity and metabolic parameters at the molecular level, we examined gene-expression profiles, and found enhanced expression of a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
This animal study examined Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The present study evaluated the effects of H2 on NAFLD in rats and concluded that H2‑rich saline had significant therapeutic effects on NAFLD induced…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers.
This animal study examined Hydrogen gas with hypothermic machine perfusion induces lipidomic alterations in donation-after-cardiac-death rat livers. The abstract describes Rat model. The abstract reports: The analysis results revealed distinct lipid metabolic alterations across cold storage, machine perfusion (MP), and hydrogen-supplemented perfusion (MP-H2) groups compared to healthy controls. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBeneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.
This animal study examined Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 60 minutes. The abstract reports: The solution containing hydrogen gas was safe and had remarkably protective effects on the porcine during liver I/R and may be applied in the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreImage-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles.
This animal study examined Image-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles. The abstract describes Rat model. The abstract reports: However, H is sparingly soluble in water, resulting in its poor bioavailability in blood and damaged tissues. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePost-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.
This animal study examined Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. The abstract describes Rat model. The abstract reports: H was observed to ameliorate IRI in the DCD liver by maintaining microcirculation, mitochondrial functions, and redox status, as well as suppressing the cytoplasmic…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read More[Anti-injury effect of hydrogen-enriched water in a rat model of liver injury induced by aflatoxin B].
This animal study examined [Anti-injury effect of hydrogen-enriched water in a rat model of liver injury induced by aflatoxin B]. The abstract describes Rat model. The abstract reports: The results showed that, compared with the AFB group, the AFB+H group exhibited increased body weights, alleviated acute liver injury, decreased activities of serum…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors.
This randomized controlled trial examined Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 6 weeks. The abstract reports: Daily consumption of hydrogen-rich water is a potentially novel, therapeutic strategy for improving QOL after radiation exposure. Consumption of hydrogen-rich water reduces the biological…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis.
This animal study examined Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: In this study, we found that intraperitoneal injection of hydrogen-rich saline (H saline) ameliorated the mortality, cardiac dysfunction, and histopathological changes caused by DOX…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
This randomized controlled trial examined Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy. The abstract describes Human participants; sample size 80; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
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