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In mice, cCl(4) also significantly decreased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured in this model.
Read ArticleIn an animal model, liver samples in the group with inhaled hydrogen showed a statistically significant reduction in histological changes compared to the control group. These preclinical findings…
Read ArticleIn 60 patients, after treatment, the oxidative stress remained unchanged in routine treatment group, but markedly improved in hydrogen treatment group. These findings add human evidence supporting molecular…
Read ArticleThis publication examined molecular hydrogen using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read ArticleIn mice, HRW attenuated malondialdehyde level, restored glutathione depletion and increased superoxide dismutase, glutathione peroxidase and catalase activities in the liver. These preclinical findings add evidence supporting molecular…
Read ArticleIn a laboratory model, hydrogen water with high dissolved hydrogen molecule showed the same hepatocellular protective effect against ethanol as the EHW. The authors concluded that these results…
Read ArticleIn Sprague-Dawley rats, long-term HRW consumption significantly reduced LPS-induced inflammatory cell infiltration in liver tissue, suppressed the abnormal elevation of pro-inflammatory factors, and maintained relatively stable expression levels…
Read ArticleIn mice, when compared to C group, both the Model group and the HRW group showed a significant reduction in the protein expression levels of iron death-related markers…
Read ArticleIn mice, among these, Acaca, Fasn, and CD36 were decreased ( Figures 2G-I ), while Mttp and Apob were increased by high dose H₂ therapy ( Figures 2N,O…
Read ArticleIn the present study, the researchers found that HRCC treatment improved methionine-and-choline-deficient diet (MCD)-induced hepatic steatosis, increased aspartate aminotransferase and alanine aminotransferase levels, and elevated hepatic inflammatory factor…
Read ArticleIn This study utilized an in vitro model of hepatocyte lipid accumulation induced by free fatty acids (FFAs) to replicate MASLD in HepG2 cells, as shown in Figure…
Read ArticleIn mice, intraperitoneal injection of H₂ improved acute ethanol-induced liver injury in mice in a dose dependent manner, as indicated by decreasing serum ALT and AST levels, hepatic…
Read ArticleIn mice, H₂ inhalation improved gut microbiota, including increasing the abundance of Lachnospiraceae and Clostridia, and decreasing the abundance of Prevotellaceae and Muribaculaceae, and also improved intestinal barrier…
Read ArticleThis publication examined hydrogen gas using the study design reported by the authoritative source. No study results are reported because this publication is a protocol.
Read ArticleIn mice, the study verified a catalytic strategy of combining PdH nanoparticles and hydrogen inhalation, which exhibited enhanced anti-inflammatory effect for CLD treatment. These preclinical findings add evidence…
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