Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
In rats, the protective potential of the Dsol-H₂ group was superior to that of the UW group, as evidenced by lower portal venous resistance and lactate dehydrogenase leakage, a higher oxygen consumption rate, and increased bile production. These preclinical findings add evidence…
Read ArticleIn Sprague-Dawley rats, H₂ improved the hepatic histological changes and glucose tolerance, decreased the liver function parameters of plasma alanine aminotransferase and aspartate aminotransferase, and relieved liver inflammation.…
Read ArticleIn mice, H₂ treatment reduced serum TC levels in the Alcohol+H₂ group when compared with those in Alcohol group. These preclinical findings add evidence supporting molecular hydrogen's therapeutic…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Further, the article reveals ex vivo hydrogen application in liver protection. The reviewed evidence adds support for molecular hydrogen's therapeutic…
Read ArticleIn rats, the data indicate that 1-month treatment of N-acetylcysteine or hydrogen-rich saline significantly ameliorated systemic and splanchnic hyperdynamic circulation, corrected hepatic endothelial dysfunction, and decreased intrahepatic resistance…
Read ArticleIn mice, inhalation of hydrogen gas (1-4%) during the last 190min suppressed hepatic cell death, and reduced levels of serum alanine aminotransferase and hepatic malondialdehyde. These preclinical findings…
Read ArticleIn rats, inhalation of hydrogen gas at 2% concentration for 1 h significantly reduced the serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities, the expression of cytokines,…
Read ArticleIn an animal model, white blood cells in the HRS-10 group were reduced compared with the IRI group (P < 0.01). These preclinical findings add evidence supporting molecular…
Read ArticleIn rats, compared to lactated Ringer's solution, hydrogen-rich solution, or hyperoxygenated solution groups, serum AST and alanine aminotransferase levels and IL-6, tumor necrosis factor-α, and malondialdehyde expression in…
Read ArticleIn male Sprague-Dawley rats, hydrogen-rich saline attenuates BDL-induced liver damage, possibly by the reduction of inflammation and oxidative stress and the inhibition of the ERK1/2 pathway. These preclinical…
Read ArticleIn What's more, HHW ameliorated lipid accumulation by regulating miR-136/MEG3/Nrf2 axis in vitro and in vivo, miR-136 was downregulated, MEG3 as well as Nrf2 was upregulated and serum…
Read ArticleIn an animal model, kEY FINDINGS: the researchers observed that HRS visibly improved ischemia-reperfusion injury (IRI) by reducing various parameters of ERS stress as evidenced by down-regulation of…
Read ArticleIn rats, hydrogen enriched saline treatment significantly attenuated the severity of liver injury induced by ischemia-reperfusion. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the…
Read ArticleIn an animal model, hS significantly increased hydrogen concentration in liver and kidney tissues. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and…
Read ArticleIn C57BL/6 mice, hCH significantly improved liver function, reduced serum inflammatory cytokines, and inhibited hepatocyte apoptosis, and also induced the PI3K-Akt pathway activation. These preclinical findings add evidence…
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