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In rats, mDA concentration significantly increased in P15 group compared with C group at 2 h and 6 h, while its concentration is significantly reduced in the H₂ group compared with the CO₂ pneumoperitoneum group ( P < 0.05, Figure 2A and…
Read ArticleIn Wistar rats, pathological tissue sections showed liver enlargement, injury, and fatty liver in the rats; Compared with the HMD group rats, the HMD+HRW group rats showed a…
Read ArticleThis publication examined molecular hydrogen using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a…
Read ArticleIn rats, hydrogen enriched saline treatment significantly attenuated the severity of liver injury induced by ischemia-reperfusion. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. H₂ regulates the processing of pro-inflammatory components of the mast cell secretome and their entry into the extracellular matrix; this…
Read ArticleIn mice, the H₂ saturation concentrations varied among tissues significantly regardless of the concentration of H₂ inhaled, and they were detected the highest in the kidney but the…
Read ArticleIn rats, compared with CIH group, the pathology of liver microstructure were significantly improved and the serum levels of ALT, AST were significantly lower in H₂+CIH group (P<0.05);…
Read ArticleIn Human hepatoma HepG2 cells were exposed to palmitate-BSA complex after treatment with or without hydrogen for 24 h, hydrogen treatment did not alter CD36 mRNA expression but…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
Read ArticleThe researchers observed that H₂ induces the mitochondrial unfolded protein response (UPRmt) in cultured cells exposed to H₂ and in mouse liver after H₂ water administration. The authors…
Read ArticleIn rats, resuscitation with HS could protect liver of severely scalded rats with delayed resuscitation possibly by reducing infiltration of neutrophils, thus lowering the content of inflammatory cytokines,…
Read ArticleIn male Sprague-Dawley rats,, the researchers found that Pec or HAS, which enhance H₂ generation in the large intestine, alleviated hepatic IR injury. These preclinical findings add evidence…
Read ArticleIn rats, after the HRW treatment, the oxidative stress status in the liver was improved, SOD activities and MDA levels were restored, CAT activities and GSH levels were…
Read ArticleIn rats, hydrogen-rich saline plays a protective role in ANP-induced AHI through inhibiting inflammation and apoptosis, involving JNK and p38 MAPK-dependent reactive oxygen species. These preclinical findings add…
Read ArticleThese findings from a laboratory model add evidence supporting molecular hydrogen's biological and therapeutic potential in the model studied.
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