Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
This animal study examined Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice. The abstract describes Mouse model; sample size 8. The abstract reports: Western blot analysis showed that coadministration of 1.3% hydrogen gas significantly (P < 0.001) reduced the level of neuronal apoptosis to approximately 40% compared…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage.
This animal study examined Hydrogen gas post-conditioning alleviates cognitive dysfunction and anxiety-like behavior in a rat model of subarachnoid hemorrhage. The abstract describes Rat model; sample size 36. The abstract reports: Subarachnoid hemorrhage (SAH) results in high rates of mortality and lasting disability. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreGender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression.
This uncontrolled human study examined Gender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression. The abstract describes Human participants; reported duration 3 days. The abstract reports: Estrogen was responsible for increased H sensitivity in male mice with ICH. The underlying mechanism may be associated with the suppression of NF-κB signaling…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice
This animal study examined Protective Effects of Hydrogen against Low‐Dose Long‐Term Radiation‐Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. The abstract describes Mouse model. The abstract reports: And significant differences between the treatment group and the radiation-only groups were observed, showing that H could diminish the detriment induced by LDLTR and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLong-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights.
This animal study examined Long-Term Neuroprotective Effects of Hydrogen-Rich Water and Memantine in Chronic Radiation-Induced Brain Injury: Behavioral, Histological, and Molecular Insights. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 60 days. The abstract reports: Histological results revealed that HRW reduced neuronal swelling, degeneration, and loss and enhanced dendritic spine density and neurogenesis. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.
This animal study examined Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.
This animal study examined Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice. The abstract describes Mouse model. The abstract reports: Although the underlying mechanisms of bmTBI are largely unknown, some studies suggested that bmTBI is associated with blood-brain barrier disruption, oxidative stress, and edema…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreModulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats
This animal study examined Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen’s Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats. The abstract describes Rat model. The abstract reports: Experimental results showed that a 7-day MSN intervention significantly attenuated anxiety-like behaviors while reversing the synaptic deficits induced by SPS&S in prefrontal cortical regions. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation.
This animal study examined Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrate that HS restored behavioral deficits after HI in neonatal mice. These beneficial effects, in part, involve promoting microglia M2 polarization and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvidence that hydrogen peroxide, a component of oxidative stress, induces high-anxiety-related behaviour in mice.
This animal study examined Evidence that hydrogen peroxide, a component of oxidative stress, induces high-anxiety-related behaviour in mice. The abstract describes Mouse model. The abstract reports: Our findings clearly showed that HO-treated mice exhibited anxiogenic behaviour in the light/dark choice test and in the hole-board test. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens.
This animal study examined Molecular hydrogen attenuates methamphetamine-induced behavioral sensitization and activation of ERK-ΔFosB signaling in the mouse nucleus accumbens. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: We found that HRS administration was able to inhibit the acquisition and transfer of 0.1 and 0.5 mg/kg METH-induced behavioral sensitization to a certain extent,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.
This randomized controlled trial examined Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life. The abstract describes Human participants; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: In healthy individuals, aging, job stress, and cognitive load over several hours also induce increases in oxidative stress, suggesting that preventing the accumulation of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAdministration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model
This animal study examined Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model. The abstract describes Mouse model. The abstract reports: We have previously demonstrated in the MIA mouse model that maternal administration of H attenuates oxidative damage and neuroinflammation, including induced pro-inflammatory cytokines and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich water on depressive-like behavior in mice.
This uncontrolled human study examined Effects of hydrogen-rich water on depressive-like behavior in mice. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen-rich saline. The abstract reports: Emerging evidence suggests that neuroinflammation and oxidative stress may be major contributors to major depressive disorder (MDD). This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring.
This animal study examined Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: Due to its anti-inflammatory and anti-oxidative effects, recent research has demonstrated that molecular hydrogen can serve as a new medical approach for depression, anxiety…. This is an automated editorial draft based on the abstract and requires source review before publication.
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