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In mice, figure 1 Hydrogen reduced infarct volume, alleviated brain edema and improved neurobehavioral deficits at 24 hours after middle cerebral artery occlusion in mice. These preclinical findings add evidence supporting molecular hydrogen's therapeutic potential within the outcomes and biological pathways measured…
Read ArticleIn male Sprague-Dawley rats, cO poisoning resulted in increased levels of malondialdehyde, 3-nitrotyrosine and 8-hydroxy-2-deoxyguanosine and markedly reduced superoxide dismutase activity at 1 and 9 days, which were…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. The medicinal value of hydrogen (H₂) was ignored prior to research illustrating that inhalation of 2% H₂ can significantly decrease…
Read ArticleIn HT22 cells in logarithmic growth phase were cultured in vitro, inverted microscopy showed that compared with the NC group, the OGD/R group had poor cell status, swollen…
Read ArticleThe hydrogen highway to reperfusion therapy. is classified as Mechanistic study using Unverified or requires review. The primary model is Model not clearly reported. Detailed outcomes require source…
Read ArticleThis narrative review examined the available molecular-hydrogen literature. Molecular hydrogen therapy with its unique biological property of selectively scavenging pathological free radicals has demonstrated therapeutic potential in innumerable…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn Sprague-Dawley rats, compared with group C and group S, HRS and EDHB injection significantly increased the number of autophagosomes and autolysosomes in the spinal cord at 14…
Read ArticleIn conclusion, hydrogen-rich saline (10 ml/kg) might reverse remifentanil-induced hyperalgesia, through regulating NR2B-containing NMDAR trafficking to control MnSOD nitration and enhance MnSOD activity. These preclinical findings add evidence…
Read ArticleThe results of the present study demonstrate that, after experimental spinal cord injury in rats, hydrogen-rich water treatment significantly decreased inflammation as evidenced by decreased IL-6 and TNF-α…
Read ArticleThe researchers observed that administration of hydrogen-rich saline decreased the number of apoptotic cells, suppressed oxidative stress, and improved locomotor functions. These preclinical findings add evidence supporting molecular…
Read ArticleIn rabbits, here, the researchers found that I/R-challenged rabbits exhibited significant spinal cord injury characterized by the decreased numbers of normal motor neurons and hind-limb motor dysfunction, which…
Read ArticleIn rats, hydrogen-rich medium attenuated the intracellular production of ROS (especially HO•), astrogliosis, and the secretion of proinflammatory cytokines in astrocytes 12 h after H₂O₂-induced injury. These preclinical…
Read ArticleIn rabbits, bolus administration of HS (10 mL) transiently increased the current to only 1/30th and 1/27th of the plateau current with 1.2% H₂ gas inhalation in two…
Read ArticleIn mice, immunohistochemical staining for the oxidative stress marker, 4-hydroxy-2-nonenal and 8-hydroxydeoxyguanosine, showed that hydrogen administration suppressed oxidative stress induced by ligation in the spinal cord and the…
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