Research-informed education, independent testing, and practical guidance across the evolving science and application of molecular hydrogen.
Explore H2HUBB articles covering molecular hydrogen research, hydrogen water, hydrogen inhalation, dosing, product testing, safety, technology, and practical education for consumers and the hydrogen industry.
This narrative review examined the available molecular-hydrogen literature. In 2019, it was reported that inhalation of 66% hydrogen increased 72-hour survival rate and improved 24-hour neurological deficits after subarachnoid hemorrhage in rats 31; however, it had no detrimental effects on subarachnoid hemorrhage…
Read ArticleIn a laboratory model, immunohistochemistry staining for fibrinogen showed significantly increased microthrombi counts in both cortex and hippocampus after SAH which was reduced with H₂ inhalation three times…
Read ArticleIn conclusion, this is the first study to use MRI to longitudinally study H₂ and H2M treatment on ischemic stroke and the first study to compare H₂ treatment…
Read ArticleIn 2 participants, this case has demonstrated that intensive consecutive therapy with oral transmucosal hydrogen formulation is a beneficial strategy with regard to the reduction of presence and…
Read ArticleThis publication is an erratum or correction associated with a molecular-hydrogen article. It does not report a new standalone experiment.
Read ArticleIn Sprague-Dawley rats, hS treatment attenuated increases in apoptosis and autophagy postburn in wounds, according to the TUNEL staining results and the expression analysis of Bax, Bcl-2, caspase-3,…
Read ArticleIn a laboratory model, all of the results indicated that hydrogen decreased the levels of reactive oxygen species, 8‑iso‑prostaglandin F2α and malondialdehyde, and promoted the UVB exposure‑induced expression…
Read ArticleIn 22 patients with PU were recruited in the present study, eLEVATION OF CELL VIABILITY BY PRE-IRRADIATIONAL ADMINISTRATION WITH HYDROGEN-DISSOLVED WATER TO UVA-IRRADIATED HACAT CELLS AS ASSESSED BY…
Read ArticleAt week 8, the authors' parallel-controlled trial revealed 24.4% of patients (10/41) receiving hydrogen-water bathing achieved at least 75% improvement in Psoriasis Area Severity Index (PASI) score compared…
Read ArticleIn rats, the mRNA expression of iNOS in rats with hydrogen-rich water intake was lower than that in the control group at both 3 and 7 days after…
Read ArticleIn The in vitro scratch assay showed that HW was able to diminish physical injury-induced ROS generation and promote wound healing in HGF cell monolayer sheets, lIVE/DEAD staining…
Read ArticleIn mice, the levels of Th2 cytokine, interleukin-5 (IL-5), and proinflammatory cytokines such as tumor necrosis factor-α and IL-6 in HW-fed mice were significantly lower than in control…
Read ArticleIn 15 participants, the hypothesis was that H₂, through its selective antioxidant and anti-inflammatory properties, would reduce oxidative stress, modulate inflammatory pathways, and enhance skin barrier integrity, leading…
Read ArticleIn an animal model, consistently, hydrogen decreased proliferative marker expression, including BCL2, BAX, and Ki-67, and significantly reduced ROS and inflammatory cytokines production. These preclinical findings add evidence…
Read ArticleIn a study on a squamous cell carcinoma model in mice, Dole et al 68 conducted a high-pressure hydrogen treatment and found that mice with skin squamous cell…
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